Evidence map›Paper›PMID 34196773›Full record

ArticleArchives of orthopaedic and trauma surgery2022

Femoral fractures are an indicator of increased severity of injury for road traffic collision victims: an autopsy-based case-control study on 4895 fatalities.

Leonidas Roumeliotis, Nikolaos K Kanakaris, Vasileios S Nikolaou, Nikolaos Danias, Georgios Konstantoudakis, Iordanis N Papadopoulos

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Article in Archives of orthopaedic and trauma surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Leonidas Roumeliotis4th Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, University General Hospital "Attikon", Athens, Greece. leonidasroumeliotis@yahoo.gr.ORCID http://orcid.org/0000-0001-6864-0918
Nikolaos K KanakarisLeeds Major Trauma Centre, Leeds Teaching Hospitals NHS Trust, Leeds, Yorkshire, UK.
Vasileios S Nikolaou2nd Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, "Konstantopouleio" General Hospital, Athens, Greece.
Nikolaos Danias4th Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, University General Hospital "Attikon", Athens, Greece.
Georgios Konstantoudakis4th Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, University General Hospital "Attikon", Athens, Greece.
Iordanis N Papadopoulos4th Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, University General Hospital "Attikon", Athens, Greece.
National and Kapodistrian University of Athens · GRLeeds Teaching Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe course of road traffic collision (RTC) victims with femoral fractures (FFx) from injury to death was reviewed. We sought to correlate the presence of femoral fractures with the overall severity of injury from RTCs using objective indices and to identify statistically significant associations with injuries in other organs. PATIENTS AND

methodsA case-control study based on forensic material from 4895 consecutive RTC-induced fatalities, between 1996 and 2005. Injuries were coded according to the Abbreviated Injury Scale-1990 Revision (AIS-90), and the Injury Severity Score (ISS) was calculated. Victims were divided according to the presence of femoral fractures in all possible anatomic locations or not. Univariate comparisons and logistic regression analysis for probabilities of association as odds ratios (OR) were performed.

resultsThe FFx group comprised 788 (16.1%) victims. The remaining 4107 victims constituted the controls. The FFx group demonstrated higher ISS (median 48 vs 36, p < 0.001) and shorter post-injury survival times (median 60 vs 85 min, p < 0.001). Presence of bilateral fractures (15.5%) potentiated this effect (median ISS 50 vs 43, p = 0.006; median survival time 40 vs 65, p = 0.0025; compared to unilateral fractures). Statistically significant associations of FFx were identified with AIS2-5 thoracic trauma (OR 1.43), AIS2-5 abdominal visceral injuries (OR 1.89), AIS1-3 skeletal injuries of the upper (OR 2.7) and lower limbs (OR 3.99) and AIS2-5 of the pelvis (OR 2.75) (p < 0.001). In the FFx group, 218 (27.7%) victims survived past the emergency department and 116 (53.2%) underwent at least one surgical procedure. Complications occurred in 45.4% of hospitalized victims, the most common being pneumonia (34.8%).

conclusionThis study has documented that femoral fractures are associated with increased severity of injury, shorter survival times and higher incidence of associated thoracic, abdominal and skeletal extremity injuries, compared to controls. These findings should be considered for an evidence-based upgrading of trauma care.

Indexed as

Accidents, TrafficFemoral FracturesAutopsyCase-Control StudiesHumansInjury Severity ScoreAbbreviated Injury ScaleAutopsyFemoral fracturesInjury Severity ScoreRoad traffic collisionTrauma registries

Identifiers

PMID34196773
OpenAlexW3175999392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.