ReviewJournal of animal science2021
Effect of feed restriction on dairy cow milk production: a review.
Review in Journal of animal science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Supplementation of Rumen-Protected Methionine to Heat-Stressed Transition Cows Impacts Mammary Gland Cell Dynamics and Gene Expression.Animals : an open access journal from MDPI · 2026Article
- Analytical Technologies for Milk Component Analysis: A Review of Progress and Challenges.Foods (Basel, Switzerland) · 2026Review
- Milking dynamics following individual quarter dry-off in Holstein cows in an automatic milking system.JDS communications · 2026Article
- Identification of key factors causing ketosis in dairy cows with low feed intake.Animal biotechnology · 2025Article
- Energy Intake During the Transition Period Triggers Substantial Impacts on Body Weight, Milk Production Efficiency, Milk Composition and Blood Biochemical Constituents in Fat-Tailed Ewes.Veterinary medicine and science · 2025Article
- Maternal Hydroxytyrosol Supplementation Enhances Antioxidant Capacity and Immunometabolic Adaptations in Nutrient-Restricted Beef Cows and Their Offspring.Antioxidants (Basel, Switzerland) · 2025Article
- Effects of assisted calving and retained fetal membranes on milk production in the smallholder farming system.Veterinary and animal science · 2025Article
- BDH1 identified by transcriptome has a negative effect on lipid metabolism in mammary epithelial cells of dairy goats.BMC genomics · 2025Article
- Effects of concentrate intake on blood urea nitrogen, estrogen, and IGF-1 levels in relation to pregnancy status and milk yield in smallholder dairy cows.Open veterinary journal · 2025Article
- Comprehensive genetic analysis and predictive evaluation of milk electrical conductivity for subclinical mastitis in Chinese Holstein cows.BMC genomics · 2024Article
- Article
- The Most Important Metabolic Diseases in Dairy Cattle during the Transition Period.Animals : an open access journal from MDPI · 2024Review
- Cow's Milk: A Benefit for Human Health? Omics Tools and Precision Nutrition for Lactose Intolerance Management.Nutrients · 2024Review
- Short-term feed restriction induces inflammation and an antioxidant response via cystathionine-β-synthase and glutathione peroxidases in ruminal epithelium from Angus steers.Journal of animal science · 2024Article
- Multi-omics reveals the mechanism of rumen microbiome and its metabolome together with host metabolome participating in the regulation of milk production traits in dairy buffaloes.Frontiers in microbiology · 2024Article
- MiRNome variations in milk fractions during feed restrictions of different intensities in dairy cows.BMC genomics · 2023Article
- The effect of N-arachidonoylethanolamide administration on energy and fat metabolism of early lactating dairy cows.Scientific reports · 2023Article
- Polymorphism at theAnimals : an open access journal from MDPI · 2023Article
- Effects of Roughage on the Lipid and Volatile-Organic-Compound Profiles of Donkey Milk.Foods (Basel, Switzerland) · 2023Article
- Alterations in ileal transcriptomics during an intestinal barrier challenge in lactating Holstein cows fed a Saccharomyces cerevisiae fermentation product identify potential regulatory processes.Journal of animal science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the dairy cow, negative energy balance affects milk yield and composition as well as animal health. Studying the effects of negative energy balance on dairy cow milk production is thus essential. Feed restriction (FR) experiments attempting to reproduce negative energy balance by reducing the quantity or quality of the diet were conducted in order to better describe the animal physiology changes. The study of FR is also of interest since with climate change issues, cows may be increasingly faced with periods of drought leading to a shortage of forages. The aim of this article is to review the effects of FR during lactation in dairy cows to obtain a better understanding of metabolism changes and how it affects mammary gland activity and milk production and composition. A total of 41 papers studying FR in lactating cows were used to investigate physiological changes induced by these protocols. FR protocols affect the entire animal metabolism as indicated by changes in blood metabolites such as a decrease in glucose concentration and an increase in non-esterified fatty acid or β-hydroxybutyrate concentrations; hormonal regulations such as a decrease in insulin and insulin-like growth factor I or an increase in growth hormone concentrations. These variations indicated a mobilization of body reserve in most studies. FR also affects mammary gland activity through changes in gene expression and could affect mammary cell turnover through cell apoptosis, cell proliferation, and exfoliation of mammary epithelial cells into milk. Because of modifications of the mammary gland and general metabolism, FR decreases milk production and can affect milk composition with decreased lactose and protein concentrations and increased fat concentration. These effects, however, can vary widely depending on the type of restriction, its duration and intensity, or the stage of lactation in which it takes place. Finally, to avoid yield loss and metabolic disorders, it is important to identify reliable biomarkers to monitor energy balance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.