Evidence map›Paper›PMID 34196474›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Neutrophil Delivered Hollow Titania Covered Persistent Luminescent Nanosensitizer for Ultrosound Augmented Chemo/Immuno Glioblastoma Therapy.

Yujie Li, Xucong Teng, Yongji Wang, Chunrong Yang, Xiuping Yan, Jinghong Li

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 83 citations in OpenAlex.

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  11. Harnessing myeloid cells in cancer.Molecular cancer · 2025
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  17. VISTA antibody-loaded FeMaterials today. Bio · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yujie LiDepartment of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, 100084, P. R. China.
Xucong TengDepartment of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, 100084, P. R. China.
Yongji WangDepartment of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, 100084, P. R. China.
Chunrong YangDepartment of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, 100084, P. R. China.
Xiuping YanState Key Laboratory of Food Science and Technology, International Joint Laboratory on Food Safety, Jiangnan University, Wuxi, 214122, China.
Jinghong LiDepartment of Chemistry, Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing, 100084, P. R. China.ORCID 0000-0002-0750-7352
Tsinghua University · CNJiangnan University · CN

Funding

National Natural Science Foundation of China 21621003National Natural Science Foundation of China 22034004Strategic Priority Research Program of Chinese Academy of Sciences XDB36000000Tsinghua University Spring Breeze Fund 2020Z99CFZ019
6 · The paper itself

Abstract

Glioblastoma (GBM) is the most malignant brain tumor with unmet therapeutic demand. The blood-brain-barrier (BBB) and tumor heterogeneity limit the treatment effectiveness of various interventions. Here, an ultrasound augmented chemo/immuno therapy for GBM using a neutrophil-delivered nanosensitizer, is developed. The sensitizer is composed of a ZnGa

Indexed as

AnimalsAntineoplastic AgentsBrain NeoplasmsDisease Models, AnimalDrug CarriersDrug Delivery SystemsGlioblastomaImmune Checkpoint InhibitorsImmunotherapyLuminescenceMiceMice, NudeNanocapsulesNeutrophilsTitaniumUltrasonic TherapyAntineoplastic AgentsDrug CarriersImmune Checkpoint InhibitorsNanocapsulesTitaniumtitanium dioxideglioblastomamultimodal therapypersistent luminescent phosphortitanium dioxide, ultrasound

Identifiers

PMID34196474
PMCPMC8425909
OpenAlexW3174267329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.