ArticleCerebral cortex (New York, N.Y. : 1991)2021
Cortical Morphology in Autism: Findings from a Cortical Shape-Adaptive Approach to Local Gyrification Indexing.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Cortical Thickness and Curvature in Autism and ADHD: A Mega-Analysis.bioRxiv : the preprint server for biology · 2026Article
- Long-term effects of preterm birth on cortical folding trajectories in early childhood.Brain communications · 2026Article
- Cerebral blood flow changes and their genetic mechanisms in autism spectrum disorder: a combined neuroimaging and transcriptome study.European archives of psychiatry and clinical neuroscience · 2025Article
- Ultra-high resolution imaging of laminar thickness in face-selective cortex in autism.Cognitive, affective & behavioral neuroscience · 2025Article
- Insular functional connectivity in autistic and non-autistic development.Biological psychology · 2025Article
- Identifying Distinct Developmental Patterns of Brain Complexity in Autism: A Cross-Sectional Cohort Analysis Using the Autism Brain Imaging Data Exchange.Psychiatry and clinical neurosciences · 2025Article
- Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer's disease.Frontiers in aging neuroscience · 2025Article
- Unsupervised Dimensionality Reduction Techniques for the Assessment of ASD Biomarkers.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2025Article
- Brain-charting autism and attention deficit hyperactivity disorder reveals distinct and overlapping neurobiology.medRxiv : the preprint server for health sciences · 2023Article
- Application of Multimodal MRI in the Early Diagnosis of Autism Spectrum Disorders: A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Cholinergic basal forebrain atrophy in Parkinson's disease with freezing of gait.Annals of clinical and translational neurology · 2023Article
- Sex-dependent structure of socioemotional salience, executive control, and default mode networks in preschool-aged children with autism.NeuroImage · 2022Article
- Morphological and Functional Changes of Cerebral Cortex in Autism Spectrum Disorder.Innovations in clinical neuroscienceReview
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Authors and funding
14 authors.
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Abstract
It has been challenging to elucidate the differences in brain structure that underlie behavioral features of autism. Prior studies have begun to identify patterns of changes in autism across multiple structural indices, including cortical thickness, local gyrification, and sulcal depth. However, common approaches to local gyrification indexing used in prior studies have been limited by low spatial resolution relative to functional brain topography. In this study, we analyze the aforementioned structural indices, utilizing a new method of local gyrification indexing that quantifies this index adaptively in relation to specific sulci/gyri, improving interpretation with respect to functional organization. Our sample included n = 115 autistic and n = 254 neurotypical participants aged 5-54, and we investigated structural patterns by group, age, and autism-related behaviors. Differing structural patterns by group emerged in many regions, with age moderating group differences particularly in frontal and limbic regions. There were also several regions, particularly in sensory areas, in which one or more of the structural indices of interest either positively or negatively covaried with autism-related behaviors. Given the advantages of this approach, future studies may benefit from its application in hypothesis-driven examinations of specific brain regions and/or longitudinal studies to assess brain development in autism.
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