Evidence map›Paper›PMID 34195694›Full record

ReviewFaculty reviews2021

Recent advances: fertility preservation and fertility restoration options for males and females.

Chatchanan Doungkamchan, Kyle E Orwig

Abstract readReview
In one paragraph

Review in Faculty reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Review
  7. Cells · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chatchanan DoungkamchanMolecular Genetics and Developmental Biology Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.
Kyle E OrwigMolecular Genetics and Developmental Biology Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA.ORCID https://orcid.org/0000-0002-7952-8419

Funding

Project IIIP50HD096723 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Kyle Edwin Orwig · 2019 to 2026
$15.0M
Transplant CoreP01HD075795 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ORWIG, KYLE EDWIN · 2014 to 2018
$7.0M
Cellular Mechanisms of Chemotherapy-induced Male Infertility: Stem Cell or Niche?R01HD076412 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ORWIG, KYLE EDWIN · 2014 to 2018
$3.0M
Improving Fertility Preservation in Boys with CancerR01HD092084 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI ORWIG, KYLE EDWIN · 2017 to 2019
$1.1M
NICHD NIH HHS P01 HD075795NICHD NIH HHS P50 HD096723NICHD NIH HHS R01 HD076412NICHD NIH HHS R01 HD092084
6 · The paper itself

Abstract

Fertility preservation is the process of saving gametes, embryos, gonadal tissues and/or gonadal cells for individuals who are at risk of infertility due to disease, medical treatments, age, genetics, or other circumstances. Adult patients have the options to preserve eggs, sperm, or embryos that can be used in the future to produce biologically related offspring with assisted reproductive technologies. These options are not available to all adults or to children who are not yet producing mature eggs or sperm. Gonadal cells/tissues have been frozen for several thousands of those patients worldwide with anticipation that new reproductive technologies will be available in the future. Therefore, the fertility preservation medical and research communities are obligated to responsibly develop next-generation reproductive technologies and translate them into clinical practice. We briefly describe standard options to preserve and restore fertility, but the emphasis of this review is on experimental options, including an assessment of readiness for translation to the human fertility clinic.

Indexed as

cryopreservationfemale fertility preservationFertility preservationmale fertility preservationovarian tissue cryopreservationstem cellstesticular tissue cryopreservationtransplantation

Identifiers

PMID34195694
PMCPMC8204761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.