ArticleMayo Clinic proceedings. Innovations, quality & outcomes2021
Multimodal Analgesia Decreases Postoperative Opioid Consumption in Living Liver Donation.
Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Postoperative complications after vacuum-assisted excision of benign breast tumors and their associated risk factors.Medicine · 2026Article
- Impact of multimodal analgesia nursing on postoperative pain and recovery outcomes after hepatectomy.Medicine · 2026Article
- Comparison of Enhanced Recovery After Surgery guideline-based multimodal analgesia with patient-controlled morphine analgesia for length of stay after spine instrumentation surgeries - A randomised controlled trial.Indian journal of anaesthesia · 2025Article
- Clinical Trial Study Protocol: A Prospective Blinded, Randomized, Controlled Clinical Trial Protocol to Assess the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block on Postoperative Analgesia and Recovery Quality in Laparoscopic Donor Hepatectomy.Journal of pain research · 2024Article
- Acute postoperative pain management after living donor hepatectomy during the transition from an open to minimally invasive surgical approach.Saudi journal of anaesthesiaArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effects of multimodal analgesia on postoperative opioid consumption and perioperative pain management in patients undergoing living liver donation.
methodsA retrospective study was conducted of 129 patients who underwent living liver donation between 2006 and 2015. Patients were separated into 2 cohorts, pre-multimodal analgesia and multimodal analgesia, to allow intergroup analysis. All patients received an intrathecal opioid injection and underwent donor hepatectomy. Primary outcome data compared opioid consumption in oral morphine equivalents for postoperative days (PODs) 0 to 4 between the cohorts. Secondary outcomes compared yearly averaged cumulative opioid consumption on PODs 0 to 4 in oral morphine equivalents; yearly averaged numeric rating scale pain scores; hospital length of stay; and percentage of patients receiving intravenous ketorolac, ketamine, or transversus abdominis plane blocks.
resultsFor PODs 0 to 4, a 50% reduction in overall opioids administered postoperatively (359 mg vs 179 mg;
conclusionImplementation of multimodal analgesia to manage perioperative pain in living liver donation resulted in a 50% reduction of postoperative opioid consumption. Clinically satisfactory average pain scores were maintained for PODs 0 to 4.
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