Evidence map›Paper›PMID 34195548›Full record

ArticleMayo Clinic proceedings. Innovations, quality & outcomes2021

Changing Drivers of Mortality Among Patients Referred for Cardiac Stress Testing.

Alan Rozanski, Heidi Gransar, Sean W Hayes, John D Friedman, Louise E J Thomson, Daniel S Berman

Open access · goldAbstract read
In one paragraph

Article in Mayo Clinic proceedings. Innovations, quality & outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Increasing frequency of dyspnea among patients referred for cardiac stress testing.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  2. Decline in typical angina among patients referred for cardiac stress testing.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alan RozanskiDivision of Cardiology and Department of Medicine, Mount Sinai Morningside Hospital, Mount Sinai Heart, and the Icahn School of Medicine at Mount Sinai, New York, NY.
Heidi GransarDepartment of Imaging, Department of Medicine, and Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
Sean W HayesDepartment of Imaging, Department of Medicine, and Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
John D FriedmanDepartment of Imaging, Department of Medicine, and Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
Louise E J ThomsonDepartment of Imaging, Department of Medicine, and Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
Daniel S BermanDepartment of Imaging, Department of Medicine, and Burns and Allen Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA.
Cedars-Sinai Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify temporal shifts in coronary artery disease (CAD) risk factor profiles, clinical parameters, and corresponding mortality rates among patients referred for radionuclide stress testing over 22 years. PATIENTS AND

methodsWe assessed 39,750 patients with suspected CAD ("diagnostic" patients) and 10,982 patients with known CAD who underwent radionuclide stress testing between January 2, 1991, and December 31, 2012, and were followed up for at least 5 years (median, 12.7 years).

resultsAmong both diagnostic patients and those with known CAD, there was a marked temporal decline in typical angina and myocardial ischemia. However, several risk factors for disease progressively increased, including diabetes, obesity, and hypertension. In addition, the need to perform pharmacological testing in lieu of exercise increased markedly between the first and fourth epochs among both diagnostic patients (from 26.5% [1634 of 6176] to 53.0% [5781 of 10,908];

conclusionOur findings suggest a marked contemporary shift in the drivers of all-cause mortality among patients undergoing cardiac stress tests away from such factors as typical angina and inducible myocardial ischemia, which are declining in prevalence, and toward such factors as diabetes and an inability to perform exercise, which are increasing in prevalence.

Indexed as

CAD, coronary artery diseaseCVD, cardiovascular diseaseMPI, myocardial perfusion imagingSPECT, single-photon emission computed tomography

Identifiers

PMID34195548
PMCPMC8240348
OpenAlexW3157110379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.