Evidence map›Paper›PMID 34195444›Full record

ArticleHeliyon2021

MicroRNAs expression analysis shows key affirmation of Synaptopodin-2 as a novel prognostic and therapeutic biomarker for colorectal and cervical cancers.

Md Shahadat Hossain, Mahafujul Islam Quadery Tonmoy, Md Nur Islam, Md Sajedul Islam, Ibrahim Khalil Afif, Arpita Singha Roy, Atqiya Fariha, Hasan Al Reza, Newaz Mohammed Bahadur, Md Mizanur Rahaman

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Synaptopodin-2: a potential tumor suppressor.Cancer cell international · 2023
    Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Md Shahadat HossainDepartment of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Mahafujul Islam Quadery TonmoyDepartment of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Md Nur IslamDepartment of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Md Sajedul IslamDepartment of Biochemistry & Biotechnology, University of Barishal, Barishal, Bangladesh.
Ibrahim Khalil AfifDepartment of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Arpita Singha RoyDepartment of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Atqiya FarihaDepartment of Biotechnology & Genetic Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Hasan Al RezaDepartment of Genetic Engineering and Biotechnology, University of Dhaka, Dhaka, Bangladesh.
Newaz Mohammed BahadurDepartment of Applied Chemistry and Chemical Engineering, Noakhali Science and Technology University, Noakhali, Bangladesh.
Md Mizanur RahamanDepartment of Microbiology, University of Dhaka, Dhaka, Bangladesh.
Noakhali Science and Technology University · BDUniversity of Dhaka · BDUniversity of Barishal · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs play a crucial role in tumorigenesis, tumor progression, and metastasis, and thus they contribute in development of different malignancies including cervical cancer (CC) and colorectal cancer (CRC). Through integrated strategies of computational biology, this study aims to identify prognostic biomarkers responsible for CRC and CC prognosis, and potential therapeutic agents to halt the progression of these cancers. Expression analysis of miRNA datasets of CRC and CC identified 17 differentially expressed miRNAs (DEMs).

Indexed as

BiomarkersCervical cancer (CC)Colorectal cancer (CRC)MicroRNAsSYNPO2

Identifiers

PMID34195444
PMCPMC8239731
OpenAlexW3176716104

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.