Evidence map›Paper›PMID 34195363›Full record

ArticleLaryngoscope investigative otolaryngology2021

Contrast-enhanced ultrasonography for the differential diagnosis of pleomorphic adenomas and Warthin tumors in salivary glands.

Daisuke Saito, Kiyoto Shiga, Katsunori Katagiri, Shin-Ichi Oikawa, Aya Ikeda, Kodai Tsuchida, Jun Miyaguchi, Takahiro Kusaka, Hidekatsu Kuroda, Fumiaki Takahashi

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Daisuke SaitoDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Kiyoto ShigaDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.ORCID https://orcid.org/0000-0002-7461-1352
Katsunori KatagiriDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Shin-Ichi OikawaDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Aya IkedaDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Kodai TsuchidaDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Jun MiyaguchiDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Takahiro KusakaDepartment of Head and Neck Surgery Iwate Medical University Hospital Yahaba-cho Japan.
Hidekatsu KurodaDepartment of Internal Medicine Iwate Medical University Hospital Yahaba-cho Japan.
Fumiaki TakahashiDivision of Medical Engineering, Department of Information Science Iwate Medical University Yahaba-cho Japan.
Iwate Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePleomorphic adenomas have risks of malignant transformation and post operate recurrence. Therefor it is important that diagnosing pleomorphic adenomas or Warthin tumors before an operation. We evaluated the usefulness of contrast-enhanced ultrasonography (CEUS) with Sonazoid for making differential diagnoses between pleomorphic adenomas and Warthin tumors.

methodsCEUS was performed the day before surgery in 39 patients. We compared the time-intensity curve and capillary density rate of 14 pleomorphic adenomas and 13 Warthin tumors.

resultsPleomorphic adenomas demonstrated a significantly longer time to peak intensity and lower maximum curve gradient of wash-in than Warthin tumors. The capillary density rate of Warthin tumors tended to be greater than that of pleomorphic adenomas.

conclusionsCEUS and capillary density rate analysis using Sonazoid is helpful for the differential diagnosis of pleomorphic adenomas and Warthin tumors. LEVEL OF EVIDENCE: 3b.

Indexed as

contrast‐enhanced ultrasonographydifferential diagnosispleomorphic adenomasalivary gland tumorWarthin tumor

Identifiers

PMID34195363
PMCPMC8223473
OpenAlexW3163049091

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.