Evidence map›Paper›PMID 34195346›Full record

ArticleSSM - population health2021

Association and pathways of birth in the stroke belt on old age dementia and stroke Mortality.

Michael Topping, Jinho Kim, Jason Fletcher

Open access · goldAbstract read
In one paragraph

Article in SSM - population health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Unraveling disparities in county-level dementia diagnosis prevalence across the United States.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  4. Does the southern health disadvantage extend to accelerated biological aging: evidence from the health and retirement study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  5. Cumulative loneliness and memory function among U.S. older adults: the role of depressive symptoms.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Place of Birth and Cognitive Function Among Older Americans: Findings From the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  12. Article
  13. Geographic Patterns of Dementia in the United States: Variation by Place of Residence, Place of Birth, and Subpopulation.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Michael ToppingDepartment of Sociology, University of Wisconsin-Madison, USA.
Jinho KimCenter for Demography of Health and Aging, University of Wisconsin-Madison, USA.
Jason FletcherDepartment of Sociology, University of Wisconsin-Madison, USA.
University of Wisconsin–Madison · US

Funding

Statistical Data Enclave CoreP30AG017266 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Michal Engelman · 1999 to 2026
$17.0M
The Importance of Place of Birth in Determining Old Age Cognitive HealthRF1AG062765 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI FLETCHER, JASON MICHAEL, PALLONI, ALBERTO B. · 2019 to 2019
$1.6M
NIA NIH HHS P30 AG017266NIA NIH HHS RF1 AG062765
6 · The paper itself

Abstract

This paper uses data from the Diet and Health Study (DHS) to examine associations between being born in a "stroke belt" state and old age stroke and mortality outcomes. Adding to prior work that used administrative data, our paper explores educational and health mechanisms that are both stratified by geography and by mortality outcomes. Using logistic regression, we first replicate earlier findings of elevation in risk of dementia mortality (OR 1.13, CI [1.07, 1.20]) and stroke mortality (OR 1.17, CI [1.07, 1.29]) for white individuals born in a stroke belt state. These associations are largely unaffected by controls for educational attainment or by experiences with surviving a stroke and are somewhat attenuated by controls for self-rated health status in old age. The results suggest a need to consider additional life course mechanisms in order to understand the persistent effects of place of birth on old age mortality patterns.

Indexed as

Dementia mortalityEducationGeographic variationLife courseStroke belt

Identifiers

PMID34195346
PMCPMC8233219
OpenAlexW3169432535

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.