Evidence map›Paper›PMID 34195293›Full record

ArticleJournal of diabetes research2021

Association of Cardiovascular Autonomic Neuropathy and Distal Symmetric Polyneuropathy with All-Cause Mortality: A Retrospective Cohort Study.

Orsolya E Vági, Márk M Svébis, Beatrix A Domján, Anna E Körei, Ildikó Istenes, Zsuzsanna Putz, Szilvia Mészáros, Noémi Hajdú, Magdolna Békeffy, Solomon Tesfaye and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Article
  7. Article
  8. Genetic Variants Influence the Development of Diabetic Neuropathy.International journal of molecular sciences · 2024
    Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Orsolya E VágiDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-9664-9423
Márk M SvébisDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-6624-9621
Beatrix A DomjánDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0003-1300-9859
Anna E KöreiDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0001-6201-2961
Ildikó IstenesDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0001-5582-6166
Zsuzsanna PutzDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-0674-337X
Szilvia MészárosDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-4871-6986
Noémi HajdúDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Magdolna BékeffyDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.
Solomon TesfayeRoyal Hallamshire Hospital, Sheffield, UK.ORCID https://orcid.org/0000-0003-1190-1472
Péter KemplerDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-6072-8832
Viktor J HorváthDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-7888-2651
Adam G TabákDepartment of Internal Medicine and Oncology, Semmelweis University Faculty of Medicine, Budapest, Hungary.ORCID https://orcid.org/0000-0002-6234-3936
Semmelweis University · HURoyal Hallamshire Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with diabetic cardiovascular autonomic neuropathy (CAN) have increased cardiovascular mortality. However, the association between distal symmetric polyneuropathy (DSPN) or CAN with all-cause mortality is much less investigated. Thus, we set out to examine the effect of CAN and DSPN on all-cause mortality in a well-phenotyped cohort.

methodsAll diabetes cases (

resultsAltogether,

conclusionsOur results are compatible with an increased risk of mortality in people with type 1 diabetes and DSPN. Furthermore, we report a similarly strong association between DSPN and CAN and all-cause mortality in type 2 diabetes mellitus.

Indexed as

MortalityAdultAgedAutonomic Nervous System DiseasesCardiovascular SystemCause of DeathCohort StudiesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NeuropathiesFemaleHumansMaleMiddle AgedPeripheral Nervous System DiseasesRetrospective Studies

Identifiers

PMID34195293
PMCPMC8181184
OpenAlexW3166394029

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.