ArticleERJ open research2021
Characteristics and impact of exercise-induced laryngeal obstruction: an international perspective.
Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 49 citations in OpenAlex.
- Microevolutionary divergence and plasticity of laryngeal shape in the house mouse (American journal of physiology. Regulatory, integrative and comparative physiology · 2025Article
- Continuous bronchoscopy during exercise in a pediatric patient: A case report.Physiological reports · 2025Article
- Are Athletic Coaches Aware of Exercise-Induced Laryngeal Obstruction in Children and Adolescents?Pediatric pulmonology · 2025Article
- Practice Patterns in Speech-Language Pathologist Treatment of Induced Laryngeal Obstruction.American journal of speech-language pathology · 2025Article
- Clinical Case Study: Pediatric Exercise-Induced Laryngeal Obstruction.Perspectives of the ASHA special interest groups · 2025Article
- LarynxFormer: a transformer-based framework for processing and segmenting laryngeal images.Frontiers in digital health · 2025Article
- Effects of Exercise-Induced Laryngeal Obstruction in Adolescents: A Qualitative Study.American journal of speech-language pathology · 2024Article
- Economic Burden of Induced Laryngeal Obstruction in Adolescents and Children.The Laryngoscope · 2024Article
- Feasibility of continuous bronchoscopy during exercise in the assessment of large airway movement in healthy subjects.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Anxiety, Depression, and Posttraumatic Stress Disorder in Patients With Induced Laryngeal Obstruction.JAMA otolaryngology-- head & neck surgery · 2024Article
- Prevalence and characterisation of exercise-induced laryngeal obstruction in patients with exercise-induced dyspnoea.The Journal of laryngology and otology · 2024Article
- A multidimensional strategy to managing dysfunctional breathing and exercise-induced laryngeal obstruction in adolescent athletes.BMC sports science, medicine & rehabilitation · 2024Article
- A speech therapy treatment protocol for exercise induced laryngeal obstruction.Frontiers in pediatrics · 2024Article
- The Clinical Utility of Continuous Laryngoscopy During Exercise: A Report of Two Cases.Cureus · 2023Article
- Therapy Outcomes for Teenage Athletes With Exercise-Induced Laryngeal Obstruction.American journal of speech-language pathology · 2023Article
- Vocal cord dysfunction/inducible laryngeal obstruction-2022 Melbourne Roundtable Report.Respirology (Carlton, Vic.) · 2023Review
- Diagnosis and management of allergy and respiratory disorders in sport: An EAACI task force position paper.Allergy · 2022Article
- Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'.British journal of sports medicine · 2022Review
- Diagnosis of vocal cord dysfunction / inducible laryngeal obstruction-A Delphi study protocol.PloS one · 2022Article
- Self-Reported Health in Adolescents With Exercise-Induced Laryngeal Obstruction; A Cross-Sectional Study.Frontiers in pediatrics · 2021Article
Corrections and comments
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Authors and funding
11 authors at 8 institutions in 3 countries.
Funding
Abstract
backgroundExercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathlessness and wheeze yet is frequently misdiagnosed as asthma. Insight regarding the demographic characteristics, laryngeal abnormalities and impact of EILO is currently limited, with data only available from individual centre reports. The aim of this work was to provide a broader perspective from a collaboration between multiple international expert centres.
methodsFive geographically distinct clinical paediatric and adult centres (3 Denmark, 1 UK, 1 USA) with an expertise in assessing unexplained exertional breathlessness completed database entry of key characteristic features for all cases referred with suspected EILO over a 5-year period. All included cases completed clinical asthma workup and continuous laryngoscopy during exercise (CLE) testing for EILO.
resultsData were available for 1007 individuals (n=713 female (71%)) with a median (range) age of 24 (8-76) years, and of these 586 (58%) were diagnosed with EILO. In all centres, EILO was frequently misdiagnosed as asthma; on average there was a 2-year delay to diagnosis of EILO, and current asthma medication was discontinued in 20%. Collapse at the supraglottic level was seen in 60%, whereas vocal cord dysfunction (VCD) was only detected/visualised in 18%. Nearly half (45%) of individuals with EILO were active participants in recreational-level sports, suggesting that EILO is not simply confined to competitive/elite athletes.
conclusionOur findings indicate that key clinical characteristics and the impact of EILO/VCD are similar in globally distinct regions, facilitating improved awareness of this condition to enhance recognition and avoid erroneous asthma treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.