Evidence map›Paper›PMID 34195206›Full record

ArticleFrontiers in medicine2021

Rationale and Design of Assessing the Effectiveness of Short-Term Low-Dose Lithium Therapy in Averting Cardiac Surgery-Associated Acute Kidney Injury: A Randomized, Double Blinded, Placebo Controlled Pilot Trial.

Sairah Sharif, Bohan Chen, Pamela Brewster, Tian Chen, Lance Dworkin, Rujun Gong

Abstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Kidney Injury Following Cardiac Surgery: A Review of Our Current Understanding.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  4. Dietary lithium intake, graft failure and mortality in kidney transplant recipients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sairah SharifDivision of Critical Care Medicine, St Francis Hospital, New York, NY, United States.
Bohan ChenDivision of Kidney Disease and Hypertension, Department of Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, RI, United States.
Pamela BrewsterDivision of Nephrology, Department of Medicine, University of Toledo Medical Center, Toledo, OH, United States.
Tian ChenDepartment of Mathematics and Statistics, The University of Toledo, Toledo, OH, United States.
Lance DworkinDivision of Kidney Disease and Hypertension, Department of Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, RI, United States.
Rujun GongDivision of Kidney Disease and Hypertension, Department of Medicine, Rhode Island Hospital, Brown University School of Medicine, Providence, RI, United States.

Funding

Therapeutic targeting of GSK3beta: A novel approach for podocyte protectionR01DK092485 · NIDDK · RHODE ISLAND HOSPITAL · PI GONG, RUJUN · 2011 to 2015
$1.8M
The Melanocortinergic pathway inglomerular diseaseR01DK114006 · NIDDK · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI GONG, RUJUN · 2017 to 2021
$1.8M
NIDDK NIH HHS R01 DK092485NIDDK NIH HHS R01 DK114006
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute kidney injurycardiac surgery associated acute kidney injurycardiopulmonary bypass surgeryglycogen synthase kinase 3βlithium

Identifiers

PMID34195206
PMCPMC8236527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.