Evidence map›Paper›PMID 34195014›Full record

ArticleToxicology reports2021

Genotoxic risk in humans and acute toxicity in rats of a novel oral high-dose coenzyme Q10 oleogel.

Natalia Ehrenhaus Masotta, Fabian Martinez-Perafan, Marta Ana Carballo, Susana Beatriz Gorzalczany, Ana M Rojas, Valeria P Tripodi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Natalia Ehrenhaus MasottaUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Industrias, ITAPROQ (CONICET-UBA), Int. Güiraldes 2620, Ciudad Universitaria, C1428BGA, Buenos Aires, Argentina.
Fabian Martinez-PerafanUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Instituto de Fisiopatología y Bioquímica Clínica (INFIBIOC), Departamento de Bioquímica Clínica, CIGETOX (Citogenética Humana y Genética Toxicológica), C1113AAD, Buenos Aires, Argentina.
Marta Ana CarballoUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Instituto de Fisiopatología y Bioquímica Clínica (INFIBIOC), Departamento de Bioquímica Clínica, CIGETOX (Citogenética Humana y Genética Toxicológica), C1113AAD, Buenos Aires, Argentina.
Susana Beatriz GorzalczanyUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Farmacología, C1113AAD, Buenos Aires, Argentina.
Ana M RojasUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Industrias, ITAPROQ (CONICET-UBA), Int. Güiraldes 2620, Ciudad Universitaria, C1428BGA, Buenos Aires, Argentina.
Valeria P TripodiUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Tecnología Farmacéutica, Junín 954, C1113AAD, Buenos Aires, Argentina.
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidad de Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coenzyme Q

Indexed as

ALKP, alkaline phosphataseALT, alanine aminotransferaseAST, aspartate aminotransferaseCBMNcyt, cytokinesis-block micronucleus cytomeCoQ10, coenzyme Q10EC, ethylcelluloseGenotoxicityGGT, gamma-glutamyl transferaseHigh-dose coenzyme Q10 oleogelLDH, lactate dehydrogenaseMCT, Medium-chain TriglyceridesMicronucleus cytome assayMNi, micronucleiNBUDs, nuclear budsNPBs, nucleoplasmic bridgesRat acute toxicitySerum biochemical parameters

Identifiers

PMID34195014
PMCPMC8233171
OpenAlexW3175889387

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.