Evidence map›Paper›PMID 34194912›Full record

Article3 Biotech2021

High-density information storage and random access scheme using synthetic DNA.

Shufang Zhang, Jianjun Wu, Beibei Huang, Yuhong Liu

Abstract read
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. DNA storage: The future direction for medical cold data storage.Synthetic and systems biotechnology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shufang ZhangSchool of Electrical and Information Engineering, Tianjin University, Tianjin, 300072 China.ORCID 0000-0002-9888-2587
Jianjun WuSchool of Electrical and Information Engineering, Tianjin University, Tianjin, 300072 China.ORCID 0000-0002-7150-2302
Beibei HuangSchool of Electrical and Information Engineering, Tianjin University, Tianjin, 300072 China.
Yuhong LiuComputer Science and Engineering Department, Santa Clara University, Santa Clara, CA 95053 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high-storage density, long-life cycle, and low-energy consumption of DNA molecules make it the future of next-generation storage technology. However, DNA storage has the disadvantages of high-synthesis cost and low-random access efficiency. A high-density DNA-coding scheme can effectively reduce the cost of DNA synthesis. This paper first proposes a DNA-mapping method based on codebook and a random access method for DNA information based on encoded content. The mapping method satisfies the two biological constraints of homopolymer length and GC content. The random access method can efficiently and selectively read specific files in the DNA pool. To increase storage density, convolutional neural networks are combined with mapping methods to generate base sequences. In the experiments, our method was compared with the results of existing DNA information storage methods, which showed that the proposed scheme has better information storage density.

Indexed as

DNA information storageDNA moleculesHigh densitySynthetic DNA

Identifiers

PMID34194912
PMCPMC8197696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.