Evidence map›Paper›PMID 34194907›Full record

Article3 Biotech2021

Withaferin A inhibits proliferation of human endometrial cancer cells via transforming growth factor-β (TGF-β) signalling.

Kejun Xu, Hongyan Shi, Yongming Du, Jilan Ou

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  7. Frontiers in pharmacology · 2024
    Article
  8. AshwagandhaPharmaceutics · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kejun XuDepartment of obstetrics and gynaecology, Ningbo First Hospital, NO.59 of Liuting Street, Haishu District, Ningbo, 315010 Zhejiang China.
Hongyan ShiDepartment of obstetrics and gynaecology, Ningbo First Hospital, NO.59 of Liuting Street, Haishu District, Ningbo, 315010 Zhejiang China.
Yongming DuDepartment of obstetrics and gynaecology, Ningbo First Hospital, NO.59 of Liuting Street, Haishu District, Ningbo, 315010 Zhejiang China.
Jilan OuDepartment of obstetrics and gynaecology, Ningbo First Hospital, NO.59 of Liuting Street, Haishu District, Ningbo, 315010 Zhejiang China.ORCID 0000-0002-7129-518X
Ningbo First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study was designed to evaluate the anticancer effects of withaferin A against the human endometrial cancer via modulation of transforming growth factor-β (TGF-β) signalling. The results of the present study revealed that withaferin A exerts a dose and time-dependent antiproliferative effects against the human KLE endometrial cancer cells with comparatively lower toxicity against the THESCs normal cells. The IC

Indexed as

ApoptosisEndometrial cancerTGF-β signallingWithaferin AWithanolides

Identifiers

PMID34194907
PMCPMC8192617
OpenAlexW3170292740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.