Evidence map›Paper›PMID 34194826›Full record

ArticleJournal of obesity

Lipid Accumulation Product Is More Related to Insulin Resistance than the Visceral Adiposity Index in the Maracaibo City Population, Venezuela.

Valmore Bermúdez, Juan Salazar, Jorge Fuenmayor, Manuel Nava, Ángel Ortega, Pablo Duran, Milagros Rojas, Roberto Añez, Alejandra Rivas-Montenegro, Lissé Angarita and 4 more

Abstract read
In one paragraph

Article in Journal of obesity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Valmore BermúdezUniversidad Simón Bolívar, Facultad de Ciencias de La Salud, Barranquilla, Colombia.ORCID https://orcid.org/0000-0003-1880-8887
Juan SalazarEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0003-4211-528X
Jorge FuenmayorEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0002-3685-9859
Manuel NavaEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0001-9769-1693
Ángel OrtegaEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0002-7180-4765
Pablo DuranEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0002-8030-1780
Milagros RojasEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0003-2764-8846
Roberto AñezDepartment of Endocrine and Nutrition, Gregorio Marañón General University Hospital, Madrid, Spain.ORCID https://orcid.org/0000-0001-6363-2767
Alejandra Rivas-MontenegroDepartment of Endocrine and Nutrition, Gregorio Marañón General University Hospital, Madrid, Spain.
Lissé AngaritaUniversidad Andres Bello, Carrera de Nutrición, Concepción, Chile.ORCID https://orcid.org/0000-0001-7860-5112
Maricarmen ChacínUniversidad Simón Bolívar, Facultad de Ciencias de La Salud, Barranquilla, Colombia.ORCID https://orcid.org/0000-0002-5208-9401
Clímaco CanoEndocrine and Metabolic Diseases Research Center, School of Medicine, University of Zulia, Maracaibo, Venezuela.ORCID https://orcid.org/0000-0002-8103-3714
Manuel VelascoUniversidad Central de Venezuela, Escuela de Medicina José María Vargas, Caracas, Venezuela.ORCID https://orcid.org/0000-0002-9126-9050
Joselyn RojasDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID https://orcid.org/0000-0003-4994-075X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVisceral adiposity is related to insulin resistance (IR), a metabolic state considered as a risk factor for other cardiometabolic diseases. In that matter, mathematical indexes such as the visceral adiposity index (VAI) and the lipid accumulation product (LAP) could indirectly assess IR based on visceral adiposity.

objectiveTo evaluate the association and diagnostic accuracy of VAI and LAP to diagnose IR in the adult population of Maracaibo city.

methodsThis is a cross-sectional descriptive study with multistage sampling. Receiver operating characteristic (ROC) curves were built to determine VAI and LAP cutoff points to predict IR. A set of logistic regression models was constructed according to sociodemographic, psychobiologic, and metabolic variables.

results1818 subjects were evaluated (51.4% women). The area under the curve (AUC) values for LAP and VAI were 0.689 (0.665-0.714) and 0.645 (0.619-0.670), respectively. Both indexes showed a higher IR risk in the upper tertile in bivariate analysis. However, in the logistic regression analysis for the IR risk, only the 2nd (OR: 1.91; 95% CI: 1.37-2.65;

conclusionAlthough both indexes show a low predictive capacity in individuals with IR in the Maracaibo city population, the LAP index was more strongly associated with IR.

Indexed as

Insulin ResistanceLipid Accumulation ProductAdiposityAdultBody Mass IndexCross-Sectional StudiesFemaleHumansIntra-Abdominal FatMaleVenezuela

Identifiers

PMID34194826
PMCPMC8203405

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.