Evidence map›Paper›PMID 34194822›Full record

ArticleJournal of ophthalmology2021

Acute Invasive Fungal Rhinosinusitis-Related Orbital Infection: A Single Medical Center Experience.

Yu-Fang Huang, Kai-Li Liang, Chiao-Ying Liang, Po-Chin Yang, Jun-Peng Chen, Li-Chen Wei

Open access · goldAbstract read
In one paragraph

Article in Journal of ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu-Fang HuangDepartment of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID https://orcid.org/0000-0002-4486-5116
Kai-Li LiangDepartment of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID https://orcid.org/0000-0002-2530-6685
Chiao-Ying LiangDepartment of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID https://orcid.org/0000-0001-9943-8202
Po-Chin YangCenter for Geriatrics and Gerontology, Taipei Veterans General Hospital, Taipei, Taiwan.ORCID https://orcid.org/0000-0001-6517-7606
Jun-Peng ChenBiostatistics Task Force of Taichung Veterans General Hospital, Taichung, Taiwan.
Li-Chen WeiDepartment of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID https://orcid.org/0000-0002-9781-6940
Taichung Veterans General Hospital · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsAcute invasive fungal rhinosinusitis (AIFRS) is a hazardous infectious disease with rapid progression and high mortality and morbidities. Further orbital involvement is commonly seen. This study aims to analyze risk factors, clinical characteristics, and outcomes between patients with or without orbital involvement.

methodsA retrospective review was performed in a single tertiary medical center over a span of 13 years (2005-2018). A total of 21 patients with diagnosis of AIFRS were enrolled. We reviewed the patients' basic characteristics, comorbidities, clinical presentations, image study findings, culture pathogens, and treatment outcomes and analyzed the differences between orbital-involved and orbital sparing disease.

resultsThe most common comorbidities in AIFRS were diabetes mellitus (DM) and hematological malignancy. Nine the 21 AIFRS patients had orbital-involved disease. Patients with orbital involvement had a higher prevalence of DM (

conclusionIn AIFRS patients, DM other than hematological malignancy was the main risk factor for orbital-involved disease. Patients with ethmoid, sphenoid, or frontal sinusitis had a higher possibility of orbital complication. Poor consciousness at initial presentation revealed highest possibility of rhino-orbital-cerebral fungal infection and led to death.

Identifiers

PMID34194822
PMCPMC8214473
OpenAlexW3169491485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.