Evidence map›Paper›PMID 34194642›Full record

ArticleIndian journal of orthopaedics2021

Risk Stratification Algorithm for Orthopedic Trauma Patients at Risk for Fat Embolism Syndrome.

Andrew Lowery, Vineet Naran, Robert Ames, Akul Patel, Frederick Ramsey, Bridget Slattery, Theresa Pazionis

Open access · greenAbstract read
In one paragraph

Article in Indian journal of orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Andrew LoweryTemple University School of Medicine, 3500 N Broad St, Philadelphia, PA 19140 USA.ORCID 0000-0001-9712-7099
Vineet NaranTemple University School of Medicine, 3500 N Broad St, Philadelphia, PA 19140 USA.
Robert AmesTemple University Hospital Orthopedic Surgery Department, Boyer Pavilion, 3509 N Broad St 5th Floor, Philadelphia, PA 19140 USA.
Akul PatelTemple University Hospital Orthopedic Surgery Department, Boyer Pavilion, 3509 N Broad St 5th Floor, Philadelphia, PA 19140 USA.
Frederick RamseyDepartment of Clinical Sciences, Temple University School of Medicine, Boyer Pavilion, 3509 N Broad St 5th Floor, Philadelphia, PA 19140 USA.
Bridget SlatteryTemple University Hospital Orthopedic Surgery Department, Boyer Pavilion, 3509 N Broad St 5th Floor, Philadelphia, PA 19140 USA.
Theresa PazionisTemple University Hospital Orthopedic Surgery Department, Boyer Pavilion, 3509 N Broad St 5th Floor, Philadelphia, PA 19140 USA.
Temple University Hospital · USTemple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFat embolism syndrome (FES) is commonly reported in the setting of long bone and pelvic fractures, but the etiology and pathogenesis are unclear. The aim of this study was to identify clinical characteristics and laboratory findings that may place orthopedic trauma patients at a higher risk of developing FES.

methodsElectronic medical records were reviewed of all patients aged 18-89 years from 2015 to 2020 with a mention of FES in the patient chart who met Gurd and Wilson's criteria for diagnosis after experiencing orthopedic trauma. A 3:1 matched pair analysis was performed between FES patients and those with similar age, gender, and FES-associated fracture (femur, tibia, humerus, or pelvis fracture).

results18 patients with FES who met inclusion criteria were identified. Hypomagnesemia (OR = 7.43), hyperphosphatemia (OR = 6.24), hypoalbuminemia (OR = 3.78), blunt traumatic mechanism of injury (OR = 7.16) and a greater number of bones fractured (Avg/SD = 2.89/1.53) were seen more often in FES patients (all

conclusionFindings of this study suggest that patients with hypomagnesemia, hyperphosphatemia, hypoalbuminemia, a blunt trauma mechanism of injury, and an increased number of bones fractured are at increased risk for the development of FES. This may be related to their roles in physiologic oncotic pressure and inflammatory response, and thus further investigation of these variables is necessary for the evaluation of FES prevention. LEVEL OF EVIDENCE: Level 3.

Indexed as

Blunt traumaFat embolism syndromeFESHyperphosphatemiaHypoalbuminemiaHypomagnesemia

Identifiers

PMID34194642
PMCPMC8192641
OpenAlexW3128652136

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.