Evidence map›Paper›PMID 34194608›Full record

ArticleOxidative medicine and cellular longevity2021

RIPK3-Mediated Necroptosis in Diabetic Cardiomyopathy Requires CaMKII Activation.

Yun Chen, Xinshuai Li, Yuyun Hua, Yue Ding, Guoliang Meng, Wei Zhang

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

  1. [Melatonin alleviates cardiomyocyte necroptosis in diabetic mice by inhibiting the STING signaling pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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  10. The role of regulated necrosis in diabetes and its complications.Journal of molecular medicine (Berlin, Germany) · 2024
    Review
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  20. The Role of HInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yun ChenDepartment of Pharmacology, School of Pharmacy, Nantong University, Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province, Nantong, 226001 Jiangsu, China.ORCID https://orcid.org/0000-0001-6733-4820
Xinshuai LiDepartment of Pharmacology, School of Pharmacy, Nantong University, Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province, Nantong, 226001 Jiangsu, China.ORCID https://orcid.org/0000-0002-7198-9288
Yuyun HuaDepartment of Pharmacology, School of Pharmacy, Nantong University, Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province, Nantong, 226001 Jiangsu, China.ORCID https://orcid.org/0000-0003-0558-7253
Yue DingDepartment of Pharmacology, School of Pharmacy, Nantong University, Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province, Nantong, 226001 Jiangsu, China.ORCID https://orcid.org/0000-0001-5268-3809
Guoliang MengDepartment of Pharmacology, School of Pharmacy, Nantong University, Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province, Nantong, 226001 Jiangsu, China.ORCID https://orcid.org/0000-0002-8523-6543
Wei ZhangDepartment of Pharmacology, School of Pharmacy, Nantong University, Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province, Nantong, 226001 Jiangsu, China.ORCID https://orcid.org/0000-0003-4410-9879
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of Ca

Indexed as

AnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Diabetes ComplicationsDiabetic CardiomyopathiesDisease Models, AnimalHumansMaleMiceMice, KnockoutNecroptosisReceptor-Interacting Protein Serine-Threonine KinasesCalcium-Calmodulin-Dependent Protein Kinase Type 2Receptor-Interacting Protein Serine-Threonine KinasesRipk3 protein, mouse

Identifiers

PMID34194608
PMCPMC8203407
OpenAlexW3170959320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.