Evidence map›Paper›PMID 34194552›Full record

ArticleExperimental and therapeutic medicine2021

Knockdown of lncRNA NORAD inhibits the proliferation, inflammation and fibrosis of human mesangial cells under high-glucose conditions by regulating the miR-485/NRF1 axis.

Linna Wang, Xiaoying Yuan, Lifeng Lian, Huali Guo, Hongxia Zhang, Minghui Zhang

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Long Non-Coding RNAs in the Pathogenesis of Diabetic Kidney Disease.Frontiers in cell and developmental biology · 2022
    Review
  11. Lnc90386 Sponges miR-33-5p to MediateFrontiers in immunology · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Linna WangDepartment of Nephrology, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Xiaoying YuanDepartment of Nephrology, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Lifeng LianLaboratory Department, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Huali GuoBlood Purification Center, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Hongxia ZhangDepartment of Nephrology, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Minghui ZhangDepartment of Nephrology, Shengli Oilfield Central Hospital, Dongying, Shandong 257000, P.R. China.
Shengli Oilfield Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) serve major roles in diabetic nephropathy (DN). The present study investigated the regulatory mechanism of lncRNA non-coding RNA activated by DNA damage (NORAD) on DN

Indexed as

diabetic nephropathyhigh-glucosemicroRNA-485non-coding RNA activated by DNA damagenuclear respiratory factor 1

Identifiers

PMID34194552
PMCPMC8237396
OpenAlexW3166643582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.