Evidence map›Paper›PMID 34194516›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Preliminary Study on the

Ming Zhu, Weiwei Han, Yang Ling, Qiufeng Qi, Yaping Zhang, Yun Peng, Lin Chen, Yanqing Bao, Yongping Liu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ming ZhuClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.ORCID https://orcid.org/0000-0002-6843-8274
Weiwei HanEmergency Department, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.
Yang LingClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.
Qiufeng QiClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.
Yaping ZhangClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.
Yun PengClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.
Lin ChenMedical School, Soochow University, Suzhou 215123, China.
Yanqing BaoClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.
Yongping LiuClinical Oncology Laboratory, Changzhou Tumor Hospital Affiliated to Soochow University, Changzhou 213032, China.ORCID https://orcid.org/0000-0003-3755-6849
Soochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the

methodsCell viability was detected by the Cell Counting Kit-8 (CCK-8) assay. Cell cycle distribution and apoptosis were detected using flow cytometry. The THP-1 human monocytic cell line was used as a source of monocytic effector cells for analyzing proliferation and dendritic cell (DC) induction. Enzyme-linked immunosorbent assay was used to detect cytokine production, and multicolor flow cytometry was used to study the phenotype and functionality of THP-1 DCs.

resultsA high concentration (>10 mg/mL) of

conclusionsOur findings suggest that NVD not only directly inhibits the growth of gastric cancer cells but also exerts indirect antitumor effects by enhancing immune function. These results provide an important theoretical basis for the clinical application of

Identifiers

PMID34194516
PMCPMC8203390
OpenAlexW3169874861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.