Evidence map›Paper›PMID 34194428›Full record

ArticleFrontiers in immunology2021

TLR2 Regulates Mast Cell IL-6 and IL-13 Production During

Rodolfo Soria-Castro, Ángel R Alfaro-Doblado, Gloria Rodríguez-López, Marcia Campillo-Navarro, Yatsiri G Meneses-Preza, Adrian Galán-Salinas, Violeta Alvarez-Jimenez, Juan C Yam-Puc, Rosario Munguía-Fuentes, Adriana Domínguez-Flores and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
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  4. Recent Advances in Host Immune Mechanisms AgainstJournal of inflammation research · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Frontiers in immunology · 2023
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Rodolfo Soria-CastroDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Ángel R Alfaro-DobladoDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Gloria Rodríguez-LópezDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Marcia Campillo-NavarroResearch Coordination, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
Yatsiri G Meneses-PrezaDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Adrian Galán-SalinasDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Violeta Alvarez-JimenezUnidad de Citometría de Flujo, Lab de Biología Molecular y Bioseguridad Nivel 3, Centro Médico Naval, Secretaría de Marina (SEMAR), Mexico City, Mexico.
Juan C Yam-PucInstitute of Immunology and Immunotherapy, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Rosario Munguía-FuentesDepartamento de Ciencias Básicas, Unidad Profesional Interdisciplinaria en Ingeniería y Tecnologías Avanzadas, Instituto Politécnico Nacional (UPIITA-IPN), Mexico City, Mexico.
Adriana Domínguez-FloresDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Sergio Estrada-ParraDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Sonia M Pérez-TapiaDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Alma D Chávez-BlancoSubdirección de Investigación Básica, Instituto Nacional de Cancerología (INCan), México City, Mexico.
Rommel Chacón-SalinasDepartamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB-IPN), Mexico City, Mexico.
Instituto Politécnico Nacional · MXInstitute for Social Security and Services for State Workers · MXInstituto Nacional de Cancerología · MXUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell DegranulationCells, CulturedCytokinesEnzyme ActivationHost-Pathogen InteractionsInterleukin-13Interleukin-6Listeria monocytogenesMast CellsMiceMice, Inbred C57BLNF-kappa Bp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesToll-Like Receptor 2CytokinesInterleukin-13Interleukin-6NF-kappa Bp38 Mitogen-Activated Protein KinasesReactive Oxygen SpeciesToll-Like Receptor 2IL-13IL-6Listeria monocytogenesLLOMAPKmast cellp38toll like receptor-2

Identifiers

PMID34194428
PMCPMC8238461
OpenAlexW3166044990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.