ArticleFrontiers in aging neuroscience2021
Exercise Improves Movement by Regulating the Plasticity of Cortical Function in Hemiparkinsonian Rats.
Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- High-intensity interval training modulates neural oscillations and inter-regional connectivity in college students.BMC neuroscience · 2026Trial
- Therapeutic Mechanisms of Exercise in Parkinson's Disease.International journal of molecular sciences · 2025Review
- The hypothalamic estrogen receptor α pathway is involved in high-intensity interval training-induced visceral fat loss in premenopausal rats.Lipids in health and disease · 2025Article
- A longitudinal electrophysiological and behavior dataset for PD rat in response to deep brain stimulation.Scientific data · 2024Article
- Automatic sleep-wake classification and Parkinson's disease recognition using multifeature fusion with support vector machine.CNS neuroscience & therapeutics · 2024Article
- Physical exercise for brain plasticity promotion an overview of the underlying oscillatory mechanism.Frontiers in neuroscience · 2024Review
- Goal-directed and habitual control: from circuits and functions to exercise-induced neuroplasticity targets for the treatment of Parkinson's disease.Frontiers in neurology · 2023Review
- Exercise improves behavioral dysfunction and inhibits the spontaneous excitatory postsynaptic current of D2-medium spiny neurons.Frontiers in aging neuroscience · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aberrant cortical spike-local field potential (LFP) coupling leads to abnormal basal ganglia activity, disruption of cortical function, and impaired movement in Parkinson's disease (PD). Here, the primary motor cortex mediated plasticity mechanism underlying behavioral improvement by exercise intervention was investigated. Exercise alleviates motor dysfunction and induces neuroplasticity in PD. In this study, Sprague-Dawley (SD) rats were injected with 6-hydroxydopamine (6-OHDA) to induce unilateral nigrostriatal dopamine depletion. Two weeks later, a 4-week exercise intervention was initiated in the PD + exercise (Ex) group. Multichannel recording technology recorded spikes and LFPs in rat motor cortices, and balanced ability tests evaluated behavioral performance. The balanced ability test showed that the total crossing time/front leg error/input latency time was significantly lower in PD + Ex rats than in PD rats (
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