ArticleNature microbiology2021
The plant NADPH oxidase RBOHD is required for microbiota homeostasis in leaves.
Article in Nature microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed.
- The plant holobiont: integrating molecular priming and ecological legacies for climate-adaptive immunity.Essays in biochemistry · 2026Review
- A Bacterial Natural Product Reshapes Phyllosphere Microbiome Composition by Blocking Carotenoid Biosynthesis.bioRxiv : the preprint server for biology · 2026Article
- Metabolic feedbacks drive population dynamics and can lead to oscillations among leaf bacteria.Nature communications · 2026Article
- The plant microbiota: From theoretical advances to applications.Fundamental research · 2026Review
- Phenolic acid biosynthesis is associated with deleterious microbiome changes during Plasmodiophora brassicae-induced clubroot in pakchoi.Microbiome · 2026Article
- Reactive oxygen species in the rhizosphere orchestrate the recruitment of beneficial bacteria.The EMBO journal · 2026Article
- Upregulated jasmonate signaling shifts Arabidopsis microbiota interactions and stress adaptations through a positive feedback loop.The ISME journal · 2026Article
- Ecological and functional roles of plant microbiomes in environmental detoxification.Frontiers in microbiology · 2026Review
- Fungicides disrupt total and endophytic phyllosphere bacterial communities but a salicylic acid hyperimmune mutant shows microbiome resilience.ISME communications · 2026Article
- Wheat mycobiome dynamics driven by interseasonal crop-crop transfer and Fusarium head blight.Frontiers in microbiology · 2026Article
- Host genome and bacterial taxa shape the Arabidopsis seed microbiome.EMBO reports · 2026Article
- Article
- The class III peroxidase OsPrx20 is a key regulator of stress response and growth in rice.Plant communications · 2025Article
- Dynamic shifts in plant-microbe relationships.Plant biotechnology (Tokyo, Japan) · 2025Article
- Toward a plant biotechnological application of phyllosphere bacteria.Plant biotechnology (Tokyo, Japan) · 2025Article
- Potential and challenges for application of microbiomes in agriculture.The Plant cell · 2025Review
- The effect of developmental stages on microbiome assembly in the phyllosphere and rhizosphere of rice grown in urban area soil.Environmental microbiome · 2025Article
- A major trade-off between growth and defense in Arabidopsis thaliana can vanish in field conditions.PLoS biology · 2025Article
- Beyond defense: microbial modifications of plant specialized metabolites alter and expand their ecological functions.The New phytologist · 2025Review
- Gene editing of the E3 ligase PIRE1 fine-tunes reactive oxygen species production for enhanced bacterial disease resistance in tomato.The Plant cell · 2025Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
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Abstract
The plant microbiota consists of a multitude of microorganisms that can affect plant health and fitness. However, it is currently unclear how the plant shapes its leaf microbiota and what role the plant immune system plays in this process. Here, we evaluated Arabidopsis thaliana mutants with defects in different parts of the immune system for an altered bacterial community assembly using a gnotobiotic system. While higher-order mutants in receptors that recognize microbial features and in defence hormone signalling showed substantial microbial community alterations, the absence of the plant NADPH oxidase RBOHD caused the most pronounced change in the composition of the leaf microbiota. The rbohD knockout resulted in an enrichment of specific bacteria. Among these, we identified Xanthomonas strains as opportunistic pathogens that colonized wild-type plants asymptomatically but caused disease in rbohD knockout plants. Strain dropout experiments revealed that the lack of RBOHD unlocks the pathogenicity of individual microbiota members driving dysbiosis in rbohD knockout plants. For full protection, healthy plants require both a functional immune system and a microbial community. Our results show that the NADPH oxidase RBOHD is essential for microbiota homeostasis and emphasizes the importance of the plant immune system in controlling the leaf microbiota.
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