Evidence map›Paper›PMID 34193945›Full record

ArticleScientific reports2021

Symptom-based early-stage differentiation between SARS-CoV-2 versus other respiratory tract infections-Upper Silesia pilot study.

Justyna Mika, Joanna Tobiasz, Joanna Zyla, Anna Papiez, Małgorzata Bach, Aleksandra Werner, Michał Kozielski, Mateusz Kania, Aleksandra Gruca, Damian Piotrowski and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Justyna Mika *Department of Data Science and Engineering, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0003-4615-784X
Joanna Tobiasz *Department of Data Science and Engineering, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0002-4666-1336
Joanna Zyla *Department of Data Science and Engineering, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0002-2895-7969
Anna PapiezDepartment of Data Science and Engineering, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0003-0179-1302
Małgorzata BachDepartment of Applied Informatics, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0002-6239-7790
Aleksandra WernerDepartment of Applied Informatics, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0001-6098-0088
Michał KozielskiDepartment of Computer Networks and Systems, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0003-3573-7638
Mateusz KaniaDepartment of Graphics, Computer Vision and Digital Systems, Silesian University of Technology, Gliwice, Poland.
Aleksandra GrucaDepartment of Computer Networks and Systems, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0003-2337-1894
Damian PiotrowskiDepartment of Infectious Diseases and Hepatology, Medical University of Silesia, Katowice, Poland.
Barbara Sobala-SzczygiełDepartment of Infectious Diseases and Hepatology, Medical University of Silesia, Katowice, Poland.
Bożena WłostowskaDepartment of Infectious Diseases and Hepatology, Medical University of Silesia, Katowice, Poland.
Paweł FosznerDepartment of Graphics, Computer Vision and Digital Systems, Silesian University of Technology, Gliwice, Poland.
Marek SikoraDepartment of Computer Networks and Systems, Silesian University of Technology, Gliwice, Poland.ORCID 0000-0002-2393-9761
Joanna PolanskaDepartment of Data Science and Engineering, Silesian University of Technology, Gliwice, Poland. joanna.polanska@polsl.pl.ORCID 0000-0001-8004-9864
Jerzy JaroszewiczDepartment of Infectious Diseases and Hepatology, Medical University of Silesia, Katowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the DECODE project, data were collected from 3,114 surveys filled by symptomatic patients RT-qPCR tested for SARS-CoV-2 in a single university centre in March-September 2020. The population demonstrated balanced sex and age with 759 SARS-CoV-2( +) patients. The most discriminative symptoms in SARS-CoV-2( +) patients at early infection stage were loss of taste/smell (OR = 3.33, p < 0.0001), body temperature above 38℃ (OR = 1.67, p < 0.0001), muscle aches (OR = 1.30, p = 0.0242), headache (OR = 1.27, p = 0.0405), cough (OR = 1.26, p = 0.0477). Dyspnea was more often reported among SARS-CoV-2(-) (OR = 0.55, p < 0.0001). Cough and dyspnea were 3.5 times more frequent among SARS-CoV-2(-) (OR = 0.28, p < 0.0001). Co-occurrence of cough, muscle aches, headache, loss of taste/smell (OR = 4.72, p = 0.0015) appeared significant, although co-occurrence of two symptoms only, cough and loss of smell or taste, means OR = 2.49 (p < 0.0001). Temperature > 38℃ with cough was most frequent in men (20%), while loss of taste/smell with cough in women (17%). For younger people, taste/smell impairment is sufficient to characterise infection, whereas in older patients co-occurrence of fever and cough is necessary. The presented study objectifies the single symptoms and interactions significance in COVID-19 diagnoses and demonstrates diverse symptomatology in patient groups.

Indexed as

SARS-CoV-2Academic Medical CentersAdolescentAdultAgedAged, 80 and overAgeusiaChildChild, PreschoolCoughCOVID-19Diagnosis, DifferentialDyspneaFemaleFeverHeadache

Identifiers

PMID34193945
PMCPMC8245528

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.