ArticleHorticulture research2021
SlBBX20 interacts with the COP9 signalosome subunit SlCSN5-2 to regulate anthocyanin biosynthesis by activating SlDFR expression in tomato.
Article in Horticulture research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 70 citations in OpenAlex.
- Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis.Journal of integrative plant biology · 2026Article
- Recent progress in unraveling the molecular mechanisms of anthocyanin biosynthesis and regulation in tomato.Horticulture research · 2026Article
- MdBBX47, a B-box transcription factor directly and indirectly regulates ALA-induced anthocyanin accumulation in apple.BMC plant biology · 2026Article
- Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience.The New phytologist · 2026Review
- Review
- MdCSN5-MdIAMT module promotes anthocyanin accumulation by regulating IAA homeostasis in apple.Horticulture research · 2026Article
- SlERF.D2-mediated antagonism between ethylene and ABA signaling pathways modulates osmotic stress adaptation in tomato.Horticulture research · 2026Article
- COP9 Signalosome's Role in Plant Defense Mechanisms.Plants (Basel, Switzerland) · 2025Review
- Functional Characterization of Anthocyanin Biosynthesis-RelatedPlants (Basel, Switzerland) · 2025Article
- The light-responsive transcription factor SlBBX20 improves low-temperature resistance of Solanum lycopersicum by affecting photosynthetic capacity, antioxidant capacity, and osmotic adjustment.Plant cell reports · 2025Article
- SmCSN5 is a synergist in the transcription factor SmMYB36-mediated biosynthesis of tanshinones and phenolic acids inHorticulture research · 2025Article
- PKS1 involved in anthocyanin accumulation in red-skinned pear fruit.Plant cell reports · 2025Article
- Tissue-specific transcriptome analyses unveils candidate genes for flavonoid biosynthesis, regulation and transport in the medicinal plant Ilex asprella.Scientific reports · 2024Article
- Transcription factors LvBBX24 and LvbZIP44 coordinated anthocyanin accumulation in response to light in lily petals.Horticulture research · 2024Article
- Genetic and Biotechnological Approaches to Improve Fruit Bioactive Content: A Focus on Eggplant and Tomato Anthocyanins.International journal of molecular sciences · 2024Review
- Tomato SlWRKY3 Negatively RegulatesPlants (Basel, Switzerland) · 2024Article
- Article
- EARLY FLOWERING is a dominant gain-of-function allele of FANTASTIC FOUR 1/2c that promotes early flowering in tomato.Plant biotechnology journal · 2024Article
- miR156b-targetedHorticulture research · 2024Article
- Recent Advances in Studying the Regulation of Fruit Ripening in Tomato Using Genetic Engineering Approaches.International journal of molecular sciences · 2024Review
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anthocyanins play vital roles in plant stress tolerance and growth regulation. Previously, we reported that the photomorphogenesis-related transcription factor SlBBX20 regulates anthocyanin accumulation in tomato. However, the underlying mechanism remains unclear. Here, we showed that SlBBX20 promotes anthocyanin biosynthesis by binding the promoter of the anthocyanin biosynthesis gene SlDFR, suggesting that SlBBX20 directly activates anthocyanin biosynthesis genes. Furthermore, we found by yeast two-hybrid screening that SlBBX20 interacts with the COP9 signalosome subunit SlCSN5-2, and the interaction was confirmed by bimolecular fluorescence complementation and coimmunoprecipitation assays. SlCSN5 gene silencing led to anthocyanin hyperaccumulation in the transgenic tomato calli and shoots, and SlCSN5-2 overexpression decreased anthocyanin accumulation, suggesting thSlCSN5-2 enhanced the ubiquitination of SlBBX20 and promoted the degradation of SlBBX20 in vivo. Consistently, silencing the SlCSN5-2 homolog in tobacco significantly increased the accumulation of the SlBBX20 protein. Since SlBBX20 is a vital regulator of photomorphogenesis, the SlBBX20-SlCSN5-2 module may represent a novel regulatory pathway in light-induced anthocyanin biosynthesis.
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Registered trials
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