ArticleHorticulture research2021
Sex biased expression of hormone related genes at early stage of sex differentiation in papaya flowers.
Article in Horticulture research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- Morphological Staging and Transcriptomic Analyses Reveal Divergent Reproductive Organ Fates in Papaya Flowers.Plants (Basel, Switzerland) · 2026Article
- Integrated methylome and transcriptome analysis provides insight into DNA methylation-mediated networks in sexual dimorphism of Vernicia montana.BMC plant biology · 2026Article
- Hybridization Drives Trait Integration in Telomere-To-Telomere Apocynum Genomes.Plant biotechnology journal · 2025Article
- Spatiotemporal Transcriptomic Atlas Reveals the Regulatory Mechanisms Underlying Early Inflorescence Development and Sex Differentiation in Spinach.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Targeted Metabolites and Transcriptome Analysis Uncover the Putative Role of Auxin in Floral Sex Determination inPlants (Basel, Switzerland) · 2024Article
- The Mechanism of the Development and Maintenance of Sexual Dimorphism in the Dioecious Mulberry Plant (Biology · 2024Article
- Comparative proteomic analysis of papaya bud flowers reveals metabolic signatures and pathways driving hermaphrodite development.Scientific reports · 2024Article
- Article
- Comparative transcriptome analysis of dioecious floral development in Trachycarpus fortunei using Illumina and PacBio SMRT sequencing.BMC plant biology · 2023Article
- Genomic and Transcriptomic Insights into the Evolution and Divergence of MIKC-Type MADS-Box Genes inInternational journal of molecular sciences · 2023Article
- Transcriptome Analysis of the Late-Acting Self-Incompatibility Associated with RNase T2 Family inPlants (Basel, Switzerland) · 2023Article
- Article
- Evolution of plant sex and molecular mechanisms underlying plants sex separation.Forestry research · 2023Review
- Sex-based metabolic and microbiota differences in roots and rhizosphere soils of dioecious papaya (Frontiers in plant science · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Sex types of papaya are controlled by a pair of nascent sex chromosomes, but molecular genetic mechanisms of sex determination and sex differentiation in papaya are still unclear. We performed comparative analysis of transcriptomic profiles of male and female floral buds at the early development stage before the initiation of reproductive organ primordia at which there is no morphological difference between male and female flowers. A total of 1734 differentially expressed genes (DEGs) were identified, of which 923 showed female-biased expression and 811 showed male-biased expression. Functional annotation revealed that genes related to plant hormone biosynthesis and signaling pathways, especially in abscisic acid and auxin pathways, were overrepresented in the DEGs. Transcription factor binding motifs, such as MYB2, GAMYB, and AP2/EREBP, were enriched in the promoters of the hormone-related DEGs, and transcription factors with those motifs also exhibited differential expression between sex types. Among these DEGs, we also identified 11 genes in the non-recombining region of the papaya sex chromosomes and 9 genes involved in stamen and carpel development. Our results suggested that sex differentiation in papaya may be regulated by multiple layers of regulation and coordination and involved transcriptional, epigenetic, and phytohormone regulation. Hormones, especially ABA and auxin, transcription factors, and genes in the non-recombination region of the sex chromosome could be involved in this process. Our findings may facilitate the elucidation of signal transduction and gene interaction in sex differentiation of unisexual flowers in papaya.
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Registered trials
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