Evidence map›Paper›PMID 34193593›Full record

ArticleOccupational and environmental medicine2022

Maternal occupation as a nail technician or hairdresser during pregnancy and birth defects, National Birth Defects Prevention Study, 1997-2011.

Miriam R Siegel, Carissa M Rocheleau, Kendra Broadwater, Albeliz Santiago-Colón, Candice Y Johnson, Michele L Herdt, I-Chen Chen, Christina C Lawson, National Birth Defects Prevention Study

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Occupational and environmental medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Miriam R SiegelDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA wrm9@cdc.gov.ORCID 0000-0002-0231-2564
Carissa M RocheleauDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Kendra BroadwaterDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Albeliz Santiago-ColónWorld Trade Center Health Program, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Candice Y JohnsonDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Michele L HerdtCenter for Environmental Health, New York State Department of Health, Albany, New York, USA.
I-Chen ChenDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
Christina C LawsonDivision of Field Studies and Engineering, National Institute for Occupational Safety and Health, Cincinnati, Ohio, USA.
National Birth Defects Prevention Study
National Institute for Occupational Safety and Health · USNew York State Department of Health · US

Funding

Intramural CDC HHS CC999999NCBDD CDC HHS U01 DD001227
6 · The paper itself

Abstract

objectiveNail technicians and hairdressers may be exposed to chemicals with potential reproductive effects. While studies have examined birth defects in children of hairdressers, those in children of nail technicians have not been evaluated. We investigated associations between selected birth defects and maternal occupation as a nail technician or hairdresser versus a non-cosmetology occupation during pregnancy.

methodsWe analysed population-based case-control data from the multisite National Birth Defects Prevention Study, 1997-2011. Cases were fetuses or infants with major structural birth defects; controls were live-born infants without major birth defects. Expert raters classified self-reported maternal jobs as nail technician, combination nail technician-hairdresser, hairdresser, other cosmetology work or non-cosmetology work. We used logistic regression to calculate adjusted ORs and 95% CIs for associations between occupation during pregnancy and birth defects, controlling for age, smoking, education and race/ethnicity.

resultsSixty-one mothers worked as nail technicians, 196 as hairdressers, 39 as combination nail technician-hairdressers and 42 810 as non-cosmetologists. The strongest associations among nail technicians included seven congenital heart defect (CHD) groups (ORs ranging from 2.7 to 3.5) and neural tube defects (OR=2.6, CI=0.8 to 8.4). Birth defects most strongly associated with hairdressing included anotia/microtia (OR=2.1, CI=0.6 to 6.9) and cleft lip with cleft palate (OR=2.0, CI=1.1 to 3.7). All oral cleft groups were associated with combination nail technician-hairdresser work (ORs ranging from 4.2 to 5.3).

conclusionsSmall samples resulted in wide CIs. Still, results suggest associations between maternal nail technician work during pregnancy and CHDs and between hairdressing work and oral clefts.

Indexed as

Maternal ExposureOccupational ExposurePregnant PeopleAdultBarberingBeauty CultureCase-Control StudiesCleft LipCleft PalateCongenital AbnormalitiesCongenital MicrotiaFemaleHeart Defects, CongenitalHumansNeural Tube DefectsPregnancyepidemiologyoccupational healthreproductive medicine

Identifiers

PMID34193593
PMCPMC8991319
OpenAlexW3173682085

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.