Evidence map›Paper›PMID 34193555›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Loss of miR-183/96 Alters Synaptic Strength via Presynaptic and Postsynaptic Mechanisms at a Central Synapse.

Constanze Krohs, Christoph Körber, Lena Ebbers, Faiza Altaf, Giulia Hollje, Simone Hoppe, Yvette Dörflinger, Haydn M Prosser, Hans Gerd Nothwang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. NcRNA: key and potential in hearing loss.Frontiers in neuroscience · 2023
    Review
  7. Review
  8. Article
  9. MicroRNA-Dependent Control of Sensory Neuron Function Regulates Posture Behavior inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Constanze KrohsDivision of Neurogenetics, Department of Neuroscience, Carl von Ossietzky University Oldenburg, Oldenburg 26129, Germany.
Christoph KörberInstitute of Anatomy und Cell Biology, Department of Functional Neuroanatomy, Heidelberg University, Heidelberg 69120, Germany.
Lena EbbersDivision of Neurogenetics, Department of Neuroscience, Carl von Ossietzky University Oldenburg, Oldenburg 26129, Germany.ORCID https://orcid.org/0000-0002-1606-4274
Faiza AltafDivision of Neurogenetics, Department of Neuroscience, Carl von Ossietzky University Oldenburg, Oldenburg 26129, Germany.
Giulia HolljeDivision of Neurogenetics, Department of Neuroscience, Carl von Ossietzky University Oldenburg, Oldenburg 26129, Germany.
Simone HoppeInstitute of Anatomy und Cell Biology, Department of Functional Neuroanatomy, Heidelberg University, Heidelberg 69120, Germany.
Yvette DörflingerInstitute of Anatomy und Cell Biology, Department of Functional Neuroanatomy, Heidelberg University, Heidelberg 69120, Germany.
Haydn M ProsserWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge CB10 1SA, United Kingdom.
Hans Gerd NothwangDivision of Neurogenetics, Department of Neuroscience, Carl von Ossietzky University Oldenburg, Oldenburg 26129, Germany hans.g.nothwang@uni-oldenburg.de.ORCID https://orcid.org/0000-0001-7695-6437
Carl von Ossietzky Universität Oldenburg · DEHeidelberg University · DEWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A point mutation in miR-96 causes non-syndromic progressive peripheral hearing loss and alters structure and physiology of the central auditory system. To gain further insight into the functions of microRNAs (miRNAs) within the central auditory system, we investigated constitutive

Indexed as

AnimalsBrain StemFemaleMaleMiceMice, KnockoutMicroRNAsSynapsesSynaptic TransmissionMicroRNAsMirn183 microRNA, mouseMirn96 microRNA, mouseauditory hindbraincalyx of Heldmicro-RNAsynaptic transmission

Identifiers

PMID34193555
PMCPMC8360680
OpenAlexW3175931408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.