Evidence map›Paper›PMID 34193170›Full record

ArticleEnvironmental health : a global access science source2021

Dose-response evaluation of urinary cadmium and kidney injury biomarkers in Chinese residents and dietary limit standards.

Ying Qing, Jiaqi Yang, Yuanshen Zhu, Yongzhen Li, Weiwei Zheng, Min Wu, Gengsheng He

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
  3. Cadmium Toxicity toMolecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Molecular Mechanisms of Cadmium-Induced Toxicity and Its Modification.International journal of molecular sciences · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Cadmium Toxicity and Health Effects-A Brief Summary.Molecules (Basel, Switzerland) · 2023
    Review
  14. The Protective Potential ofInternational journal of molecular sciences · 2023
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ying QingSchool of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Jiaqi YangSchool of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Yuanshen ZhuSchool of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Yongzhen LiSchool of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Weiwei ZhengDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, 200032, China.
Min WuSchool of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China.
Gengsheng HeSchool of Public Health/Key Laboratory of Public Health Safety, Ministry of Education, Department of Nutrition and Food Science, Fudan University, No. 130 Dongan Road, Shanghai, 200032, China. gshe@shmu.edu.cn.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCadmium (Cd) is a common heavy metal that mainly causes renal damage. There is a lack of research on the large-scale and systematic evaluation of the association between urinary Cd (U-Cd) and various effect biomarkers among Chinese residents.

methodsBased on the establishment process of dietary Cd limit standards by European Food Safety Authority (EFSA), the dose-response relationships between U-Cd and four biomarkers, β

resultsAs the sensitive biomarkers of renal injury, β

conclusionThis study established an overall association between U-Cd and renal injury biomarkers, and explored the Chinese dietary Cd exposure limits, which helps improve Chinese Cd exposure risk assessment and provides a reference basis for formulating reasonable exposure standards.

Indexed as

Dietary ExposureModels, BiologicalAdultAlbuminuriaAsian Peoplebeta 2-MicroglobulinBiological MonitoringBiomarkersCadmiumChinaDose-Response Relationship, DrugEnvironmental PollutantsFemaleGlucosidasesHumansKidney Diseasesbeta 2-MicroglobulinBiomarkersCadmiumEnvironmental PollutantsGlucosidasesRetinol-Binding ProteinsBenchmark doseCadmiumEffect biomarkersTolerable daily intakeToxicokinetic model

Identifiers

PMID34193170
PMCPMC8247151
OpenAlexW3174996382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.