Evidence map›Paper›PMID 34193138›Full record

ArticleBMC health services research2021

Patient perspectives on the implementation of routinised syphilis screening with HIV viral load testing: Qualitative process evaluation of the Enhanced Syphilis Screening Among HIV-positive Men trial.

Kinnon R MacKinnon, Ramandip Grewal, Darrell Hs Tan, Rodney Rousseau, John Maxwell, Sharon Walmsley, Paul A MacPherson, Anita Rachlis, Nisha Andany, Sharmistha Mishra and 2 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC health services research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02019043 (Enhanced Syphilis Screening Among HIV-positive Men), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02019043 nacompletednot on this map

Enhanced Syphilis Screening Among HIV-positive Men (ESSAHM): Evaluation of a Clinic-based Intervention

TypeinterventionalSponsorUnity Health TorontoRan2015 to 2017Enrolled3,895ConditionsSyphilisArmsSyphilis testing with routine HIV bloodwork
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Routinized Syphilis Screening Among Men Living With Human Immunodeficiency Virus: A Stepped Wedge Cluster Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Kinnon R MacKinnonSchool of Social Work, York University, 4700 Keele Street, M3J 1P3, Toronto, Ontario, Canada.
Ramandip GrewalMAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, 30 Bond Street, M5B 1W8, Toronto, Ontario, Canada.
Darrell Hs TanMAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, 30 Bond Street, M5B 1W8, Toronto, Ontario, Canada.
Rodney RousseauDepartment of Immunology, University of Toronto, 1 King's College Cir, M5S 1A8, Toronto, Ontario, Canada.
John MaxwellAIDS Committee of Toronto, 543 Yonge Street, 4th floor, M4Y 1Y5, Toronto, Ontario, Canada.
Sharon WalmsleyDepartment of Medicine, University of Toronto, Toronto, Canada.
Paul A MacPhersonDivision of Infectious Diseases, The Ottawa Hospital, 501 Smyth Road, L1H 8L6, Ottawa, Ontario, Canada.
Anita RachlisDepartment of Medicine, University of Toronto, Toronto, Canada.
Nisha AndanyDepartment of Medicine, University of Toronto, Toronto, Canada.
Sharmistha MishraMAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, 30 Bond Street, M5B 1W8, Toronto, Ontario, Canada.
Vanessa G AllenPublic Health Ontario Laboratories, Public Health Ontario, 661 University Avenue, M5G 1M1, Toronto, Ontario, Canada.
Ann N BurchellMAP Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, 30 Bond Street, M5B 1W8, Toronto, Ontario, Canada. ann.burchell@unityhealth.to.
St. Michael's Hospital · CAUnity Health TorontoAIDS Committee of Toronto · CAOttawa Hospital · CAPublic Health Ontario · CASunnybrook Health Science Centre · CAUniversity Health Network · CAUniversity of New Brunswick · CAUniversity of Toronto · CAYork University · CA

Funding

Canadian HIV Trials Network, Canadian Institutes of Health Research Canadian HIV Trials Network, Canadian Institutes of Health ResearchCIHR Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundSyphilis infections have been on the rise, affecting men living with HIV in urban centres disproportionately. Since individuals in HIV care undergo routine blood testing, HIV clinics provide practical opportunities to conduct regular and frequent syphilis testing. Following the implementation of a routine syphilis testing intervention in HIV outpatient clinics, we conducted a qualitative process evaluation of patient experiences to measure patient acceptability, barriers to implementation, and facilitators of successful uptake.

methodsUpon completion of the trial, which took place at four HIV outpatient clinics in Toronto and Ottawa, Canada, we recruited male patients attending these clinics from November 2017 to April 2018. Interviews were conducted on-site and were audio-recorded and transcribed verbatim. All participants provided written informed consent. Interview data were analyzed using grounded theory, assessing qualitative modulators of effective uptake of routinised syphilis testing.

resultsA total of 21 male patients were interviewed. Overall, interviewees found the clinical intervention acceptable, endorsing the practice of routinising syphilis testing alongside regular viral load bloodwork. Some men preferred, based on their self-assessment of syphilis risk, to opt out of testing; we considered this as a potential barrier to uptake of population-wide routinised syphilis testing. Interviewees also identified multiple facilitators of successful uptake, including the de-stigmatising of STI testing as a consequence of the universal nature of routinised testing. Participants recommended a routinised syphilis screening intervention to give patients peace of mind surrounding their sexual health. Participants identified HIV care clinics as comfortable and efficient locations to offer testing.

conclusionsOverall, most men were in support of implementing routinised syphilis testing as part of standard HIV care. From the patient perspective, HIV care clinics are convenient places to be tested for syphilis, and the routine approach was viewed to have a de-stigmatisng effect on syphilis testing.

trial registrationClinicalTrials.gov NCT02019043; registered December 23, 2013.

Indexed as

HIV InfectionsSyphilisCanadaHomosexuality, MaleHumansMaleMass ScreeningViral LoadGrounded theoryHIV careMen’s sexual healthPatient process evaluationQualitative interviewsSexually transmitted infectionsSyphilis

Identifiers

PMID34193138
PMCPMC8243864
OpenAlexW3134786982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.