Evidence map›Paper›PMID 34192970›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2021

A novel single-tube multiplex real-time PCR assay for genotyping of thiopurine intolerance-causing variant

Xiaoyun Lian, Yanwei Li, Lan Li, Kaicheng U, Wenxia Wang, Yinmin Shi, Jiying Ma, Huijuan Wang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaoyun LianDepartment of Hematology, Shaanxi Provincial Peoples' Hospital, Xi'an 710068, China.
Yanwei LiThe National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an 710069, China.
Lan LiDepartment of Hematology, Shaanxi Provincial Peoples' Hospital, Xi'an 710068, China.
Kaicheng UAmerican Heritage School, Plantation, FL 33325, USA.
Wenxia WangThe National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an 710069, China.
Yinmin ShiThe National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an 710069, China.
Jiying MaThe National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an 710069, China.
Huijuan WangThe National Engineering Research Center for Miniaturized Detection Systems, Northwest University, Xi'an 710069, China.ORCID 0000-0002-2388-8714
Northwest University · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thiopurines are commonly used in the treatment of acute lymphoblastic leukaemia and autoimmune conditions, can be limited by myelosuppression. The

Indexed as

Real-Time Polymerase Chain ReactionAllelesGene FrequencyGenetic Predisposition to DiseaseGenotypeHeterozygoteHumansLeukopeniaNudix HydrolasesPyrophosphatasesNudix HydrolasesNUDT15 protein, humanPyrophosphatasesadverse drug reactiongenotypingNUDT15pharmacogenomicsreal-time PCRthiopurine

Identifiers

PMID34192970
PMCPMC8474986
OpenAlexW3174174403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.