Evidence map›Paper›PMID 34192270›Full record

ReviewOxford open immunology2021

The role and uses of antibodies in COVID-19 infections: a living review.

D Oliver Scourfield, Sophie G Reed, Max Quastel, Jennifer Alderson, Valentina M T Bart, Alicia Teijeira Crespo, Ruth Jones, Ellie Pring, Felix Clemens Richter, Oxford-Cardiff COVID-19 Literature Consortium and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Oxford open immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. The Seraph 100Antibodies (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

D Oliver ScourfieldDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Sophie G ReedDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Max QuastelNuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Jennifer AldersonKennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, OX3 FTY, UK.
Valentina M T BartDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Alicia Teijeira CrespoDivision of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, CF14 4XN UK.
Ruth JonesDementia Research Institute, Cardiff University, Cardiff, CF24 4HQ, UK.
Ellie PringDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.
Felix Clemens RichterKennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford, OX3 FTY, UK.ORCID https://orcid.org/0000-0002-3415-3449
Oxford-Cardiff COVID-19 Literature Consortium
Stephanie E A BurnellDivision of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, CF14 4XN, UK.ORCID https://orcid.org/0000-0003-3920-6180
Cardiff University · GBNuffield Orthopaedic Centre · GBUniversity of Oxford · GBUK Dementia Research Institute · GBNuffield Foundation · GB

Funding

Medical Research Council G0000635Medical Research Council MR/M008614/2Medical Research Council MR/W001217/1Versus Arthritis 21546Wellcome Trust 211122/Z/18/Z
6 · The paper itself

Abstract

Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.

Indexed as

antibodiesconvalescent plasmaCOVID-19long-term immunitynanobodiesSARS-CoV-2vaccines

Identifiers

PMID34192270
PMCPMC7928637
OpenAlexW3128675685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.