Evidence map›Paper›PMID 34192070›Full record

ArticleSouthern African journal of HIV medicine2021

HIV infection in Eastern and Southern Africa: Highest burden, largest challenges, greatest potential.

Erica Parker, Melinda A Judge, Eusebio Macete, Tacilta Nhampossa, Jienchi Dorward, Denise C Langa, Caroline De Schacht, Aleny Couto, Paula Vaz, Marco Vitoria and 5 more

Abstract read
In one paragraph

Article in Southern African journal of HIV medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Erica ParkerFaculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0003-0555-382X
Melinda A JudgeFaculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0002-9948-1865
Eusebio MaceteManhiça Health Research Centre, Manhiça, Mozambique.ORCID https://orcid.org/0000-0002-8071-4761
Tacilta NhampossaManhiça Health Research Centre, Manhiça, Mozambique.ORCID https://orcid.org/0000-0002-4616-8752
Jienchi DorwardNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.ORCID https://orcid.org/0000-0001-6072-1430
Denise C LangaDepartment of Surveillance, Instituto Nacional de Saúde, Maputo, Mozambique.ORCID https://orcid.org/0000-0001-6045-351X
Caroline De SchachtFriends in Global Health, Maputo, Mozambique.ORCID https://orcid.org/0000-0001-5384-2410
Aleny CoutoNational STI, HIV/AIDS Programme, Ministry of Health, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-2109-198X
Paula VazFundaçao Ariel Glaser contra o SIDA pediátrico, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-0228-5957
Marco VitoriaDepartment of HIV/AIDS, World Health Organization, Geneva, Switzerland.ORCID https://orcid.org/0000-0002-1687-6723
Lucas MolfinoMédecins Sans Frontières, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-6322-7099
Rachel T IdowuCenter for Global Health, Centers for Disease Control and Prevention, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-7274-272X
Nilesh BhattElizabeth Glaser Pediatric AIDS Foundation, Maputo, Mozambique.ORCID https://orcid.org/0000-0002-8389-7786
Denise NanicheManhiça Health Research Centre, Manhiça, Mozambique.ORCID https://orcid.org/0000-0002-4495-6325
Peter N Le SouëfFaculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia.ORCID https://orcid.org/0000-0003-0930-1654

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundThe burden of HIV is especially concerning for Eastern and Southern Africa (ESA), as despite expansion of test-and-treat programmes, this region continues to experience significant challenges resulting from high rates of morbidity, mortality and new infections. Hard-won lessons from programmes on the ground in ESA should be shared.

objectivesThis report summarises relevant evidence and regional experts' recommendations regarding challenges specific to ESA.

methodThis commentary includes an in-depth review of relevant literature, progress against global goals and consensus opinion from experts.

resultsRecommendations include priorities for essential research (surveillance data collection, key and vulnerable population education and testing, in-country testing trials and evidence-based support services to improve retention in care) as well as research that can accelerate progress towards the prevention of new infections and achieving ambitious global goals in ESA.

conclusionThe elimination of HIV in ESA will require continued investment, commitment to evidence-based programmes and persistence. Local research is critical to ensuring that responses in ESA are targeted, efficient and evaluated.

Indexed as

early diagnosisHIV epidemiologyprevention and controlpublic healthrisk factorsvulnerable populations

Identifiers

PMID34192070
PMCPMC8182467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.