ArticleHealth SA = SA Gesondheid2021
Antibiotic use amongst pregnant women in a public hospital in KwaZulu-Natal.
Article in Health SA = SA Gesondheid, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Efficacy and Safety of Meropenem in Pregnant Women with Upper Urinary Tract Infections: A Retrospective Cohort Study in Romania.Antibiotics (Basel, Switzerland) · 2026Article
- Prevalence and factors associated with the irrational use of antibiotics by pregnant women in the city of Marrakech, Morocco: a cross-sectional study.BMC pregnancy and childbirth · 2025Article
- Developmental exposure of antibiotics shortens life span and induces teratogenicity inToxicology reports · 2024Article
- Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota.Pharmacotherapy · 2023Review
- Predictors of antibiotic use in pregnant women attending Najran University Hospital, Saudi Arabia.Saudi medical journal · 2023Article
- Antibiotic safety among neonates and paediatrics in a public hospital: KwaZulu-Natal.Health SA = SA Gesondheid · 2023Article
- Prenatal Maternal Antibiotics Treatment Alters the Gut Microbiota and Immune Function of Post-Weaned Prepubescent Offspring.International journal of molecular sciences · 2022Article
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3 authors.
Funding
Abstract
backgroundAntibiotics are amongst the more frequently prescribed medicines in pregnant women and the use of antibiotics is increasing. However, with limited studies available in this population, the safe use of antibiotics in pregnancy remains a concern.
aimTo evaluate the use of antibiotics amongst pregnant women attending a public health care facility. The main objective of this study was to quantify the types of antibiotics used in pregnant women.
settingA public hospital classified as a referral hospital located in Durban, KwaZulu-Natal.
methodsDemographic and treatment information of women were collected retrospectively from January 2019 to July 2019. A total of 184 pregnant patients, who received antibiotic therapy, were included in this study. Descriptive and analytical measures were used to analyse both patient demographics and treatment variables.
resultsA total of 416 antibiotic prescriptions, issued to 184 patients, were reviewed. Penicillins (39.7%), macrolides (13.0%) and combination penicillin- and beta-lactam inhibitors (12.3%) were reported as the most commonly prescribed antibiotics. Rifamycin (2.9%), hydrazides (2.2%) and aminoglycosides (1.9%) were less frequently prescribed. Most antibiotics were prescribed for diseases of the circulatory system (36.1%).
conclusionSeveral classes of antibiotics were used in pregnancy despite the lack of available safety data and clinical evidence. Informing women of the potential side effects and keeping abreast with new information played an important role in the safe, rational and effective use of medicines that contributed to improving maternal health.
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