Evidence map›Paper›PMID 34192050›Full record

ArticleJournal of clinical and translational science2021

Modifying laboratory testing via home brew during the COVID-19 pandemic.

Jeffery H Moran, Larry Kessler, Jennifer Moylan, Craig Forrest, Karl Boehme, Josh Kennedy, Alex Greninger, Geoff Baird, Ericka Olgaard, Laura James

Abstract read
In one paragraph

Article in Journal of clinical and translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Lessons Learned from the Lessons Learned in Public Health during the First Years of COVID-19 Pandemic.International journal of environmental research and public health · 2023
    Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jeffery H MoranDepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Larry KesslerDepartment of Health Services, School of Public Health, University of Washington, Seattle, WA, USA.
Jennifer MoylanDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA.ORCID https://orcid.org/0000-0002-6065-5311
Craig ForrestDepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID https://orcid.org/0000-0002-6695-0936
Karl BoehmeDepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID https://orcid.org/0000-0003-2691-9763
Josh KennedyDepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Alex GreningerDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-7443-0527
Geoff BairdDepartment of Laboratory Medicine and Pathology, School of Medicine, University of Washington, Seattle, Washington, USA.
Ericka OlgaardDepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Laura JamesDepartments of Pharmacology and Toxicology, Microbiology, Pathology, and Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.ORCID https://orcid.org/0000-0002-4266-3924

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
CTSA Coordinating Center for Leading Innovation and Collaboration (CLIC)U24TR002260 · NCATS · UNIVERSITY OF ROCHESTER · PI OSSIP, DEBORAH J, ZAND, MARTIN S · 2017 to 2021
$19.0M
NCATS NIH HHS U24 TR002260NCATS NIH HHS UL1 TR001998NCATS NIH HHS UL1 TR002319NCATS NIH HHS UL1 TR003107
6 · The paper itself

Abstract

Rapid development and deployment of diagnostic testing for COVID-19 have been a key component of the public health response to the pandemic. Out of necessity, academic and other clinical laboratories developed laboratory testing innovations for COVID-19 to meet clinical testing demands. In addition to constraints on local testing supplies and equipment, a rapidly changing regulatory framework created challenges for translational scientists. Illustrative examples of approaches used to develop laboratory tests during the early stages of the COVID-19 pandemic demonstrate effective team science approaches to this challenging clinical care and public health emergency. These experiences and the associated lessons learned are relevant to the development of public health response plans for future pandemics.

Indexed as

COVID-19Diagnostic testslaboratory developed tests

Identifiers

PMID34192050
PMCPMC8134902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.