Evidence map›Paper›PMID 34191663›Full record

ArticleAIDS care2022

Persons living with HIV treated in acute HIV infection report good health-related quality of life in Thailand.

Orlanda Q Goh, Eugène Kroon, Carlo Sacdalan, Phillip Chan, Trevor A Crowell, Ratchapong Kanaprach, Jintanat Anonworanich, Sandhya Vasan, Albert W Wu, Nittaya Phanuphak and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

Orlanda Q GohSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.ORCID 0000-0001-8423-2703
Eugène KroonSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Carlo SacdalanSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Phillip ChanSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID 0000-0001-5947-265X
Ratchapong KanaprachSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Jintanat AnonworanichU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID 0000-0003-1369-3224
Sandhya VasanU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Albert W WuJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Nittaya PhanuphakSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Donn J ColbySEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
RV254/SEARCH 010 Study Group
Thai Red Cross Society · THHenry M. Jackson Foundation · USJohns Hopkins University · US

Funding

Therapeutic Interventions during Acute Infection to Address the CNS Reservoir forR01NS084911 · NINDS · YALE UNIVERSITY · PI ANANWORANICH, JINTANAT, SPUDICH, SERENA S · 2013 to 2017
$2.3M
NINDS NIH HHS R01 NS084911
6 · The paper itself

Abstract

The health-related quality of life (HRQoL) among persons living with HIV (PLWHA) who initiate ART during acute HIV infection (AHI) is not well studied. Participants in the SEARCH010/RV254 cohort initiated ART during AHI. They completed the Thai version of the World Health Organisation Quality of Life instrument-BREF (WHOQOL-BREF) and Patient Health Questionnaire-9 (PHQ-9) prior to ART initiation and 24 weeks later. Of 452 participants, 406 (90%) completed the WHOQOL-BREF. The median age was 26 years (IQR 22-31), and 98% were men. All WHOQOL-BREF domains demonstrated good internal consistency (Cronbach's alpha >0.70). Confirmatory factor analysis validated the WHOQOL-BREF model. 90% of Pearson correlations between domain scores and general facet items were >0.50. HRQoL in all domains was worse among those with at least moderately severe depression (PHQ-9 ≥ 10) (

Indexed as

HIV InfectionsQuality of LifeAdultFemaleHumansMalePsychometricsReproducibility of ResultsSurveys and QuestionnairesThailandWorld Health OrganizationAsianhighly active antiretroviral therapyHIVminimal clinically important differencepatient reported outcome measuresquality of life

Identifiers

PMID34191663
PMCPMC13504517
OpenAlexW3174073497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.