Evidence map›Paper›PMID 34191587›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2021

How the PhoP/PhoQ System Controls Virulence and Mg

Eduardo A Groisman, Alexandre Duprey, Jeongjoon Choi

Open access · greenAbstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 149 citations in OpenAlex.

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  12. Development of covalent inhibitors for bacterial histidine kinases.Chemical communications (Cambridge, England) · 2026
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eduardo A GroismanDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut, USA.
Alexandre DupreyDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut, USA.
Jeongjoon ChoiDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut, USA.
Yale University · US

Funding

REGULATION OF SALMONELLA VIRULENCE BY THE PHOP PROTEINR01AI049561 · NIAID · YALE UNIVERSITY · PI Eduardo Groisman · 2001 to 2026
$9.7M
NIAID NIH HHS R01 AI049561
6 · The paper itself

Abstract

The PhoP/PhoQ two-component system governs virulence, Mg

Indexed as

AnimalsBacterial ProteinsEvolution, MolecularHistidine KinaseHomeostasisHumansMagnesiumSalmonella typhimuriumSignal TransductionTranscription FactorsTranscription, GeneticVirulenceBacterial ProteinsHistidine KinaseMagnesiumPhoP protein, BacteriassrA protein, Salmonella typhimuriumTranscription Factorsacidic pHantimicrobial peptidesATPgene silencinglipopolysaccharidepromoter architectureprotein synthesisproteolysisSalmonellatwo-component system

Identifiers

PMID34191587
PMCPMC8483708
OpenAlexW3174073890

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.