Evidence map›Paper›PMID 34191531›Full record

ArticleApplied and environmental microbiology2021

Borrelia afzelii Infection in the Rodent Host Has Dramatic Effects on the Bacterial Microbiome of Ixodes ricinus Ticks.

Phineas T Hamilton, Elodie Maluenda, Anouk Sarr, Alessandro Belli, Georgia Hurry, Olivier Duron, Olivier Plantard, Maarten J Voordouw

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Article
  3. Current research in parasitology & vector-borne diseases · 2025
    Article
  4. Differential Impact of Simultaneous or Sequential Coinfections WithInternational journal of microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. What do we know about the microbiome ofFrontiers in cellular and infection microbiology · 2022
    Review
  10. Assessing Temporal Changes in Microbial Communities inFrontiers in veterinary science · 2022
    Article
  11. Changes in theFrontiers in microbiology · 2022
    Article
  12. Article
  13. Article
  14. Current debates and advances in tick microbiome research.Current research in parasitology & vector-borne diseases · 2021
    Review
  15. Ecological and evolutionary perspectives on tick-borne pathogen co-infections.Current research in parasitology & vector-borne diseases · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Phineas T HamiltonDeeley Research Centre, BC Cancer, Victoria, British Columbia, Canada.
Elodie MaluendaLaboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtelgrid.10711.36, Neuchâtel, Switzerland.
Anouk SarrLaboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtelgrid.10711.36, Neuchâtel, Switzerland.
Alessandro BelliLaboratory of Ecology and Epidemiology of Parasites, Institute of Biology, University of Neuchâtelgrid.10711.36, Neuchâtel, Switzerland.
Georgia HurryDepartment of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Olivier DuronCentre of Research in Ecology and Evolution of Diseases (CREES), Montpellier, France.
Olivier PlantardINRAE, Oniris, BIOEPAR, Nantes, France.
Maarten J VoordouwLaboratory of Ecology and Evolution of Parasites, Institute of Biology, University of Neuchâtelgrid.10711.36, Neuchâtel, Switzerland.
University of Neuchâtel · CHUniversity of Saskatchewan · CACentre National de la Recherche Scientifique · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FR

Funding

CIHR
6 · The paper itself

Abstract

The microbiome of blood-sucking arthropods can shape their competence to acquire and maintain infections with vector-borne pathogens. We used a controlled study to investigate the interactions between Borrelia afzelii, which causes Lyme borreliosis in Europe, and the bacterial microbiome of Ixodes ricinus, its primary tick vector. We applied a surface sterilization treatment to

Indexed as

Borrelia burgdorferi GroupAnimalsEthanolFemaleIxodesLarvaLyme DiseaseMiceMice, Inbred BALB CMicrobiotaNymphOvumSodium HypochloriteSterilizationEthanolSodium HypochloriteBorrelia afzeliidysbiosisegg surface sterilizationIxodes ricinusLyme diseasemicrobiometick-borne diseasevector-borne disease

Identifiers

PMID34191531
PMCPMC8388833
OpenAlexW3176055576

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.