Evidence map›Paper›PMID 34191415›Full record

ArticleArchives of endocrinology and metabolism2021

Trans Oral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) in Brazil: Safety and complications during learning curve.

Antonio Augusto Tupinambá Bertelli, Leonardo Guimarães Rangel, Renan Bezerra Lira, Marco Antonio Scirea Tesseroli, Izabella Costa Santos, Guilherme Duque Silva, Michelle Azevedo Gomes, Lucas Ribeiro Tenório, Luiz Paulo Kowalski, Antonio José Gonçalves and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Archives of endocrinology and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Transoral thyroid and parathyroid surgery in Brazil: where are we?Revista do Colegio Brasileiro de Cirurgioes · 2023
    Article
  7. Article
  8. Transoral thyroidectomy-learning curve.Archives of endocrinology and metabolism · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 2 countries.

Antonio Augusto Tupinambá BertelliDisciplina de Cirurgia de Cabeça e Pescoço, Departamento de Cirurgia, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brasil.
Leonardo Guimarães RangelUniversidade do Estado do Rio de Janeiro, RJ, Brasil.
Renan Bezerra LiraA.C. Camargo Cancer Center, São Paulo, SP, Brasil.
Marco Antonio Scirea TesseroliUnimed Chapecó Hospital, Chapecó, SC, Brasil.
Izabella Costa SantosInstituto Nacional do Câncer, Rio de Janeiro, RJ, Brasil.
Guilherme Duque SilvaServiço de Cirurgia de Cabeça e Pescoço, Hospital Central da Polícia Militar do Rio de Janeiro, Universidade do Estado do Rio de Janeiro, RJ, Brasil.
Michelle Azevedo GomesHospital Federal de Bonsucesso e Universidade do Estado do Rio de Janeiro, RJ, Brasil.
Lucas Ribeiro TenórioDisciplina de Cirurgia de Cabeça e Pescoço, Departamento de Cirurgia, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brasil, tenoriolr@gmail.com.
Luiz Paulo KowalskiA.C. Camargo Cancer Center, São Paulo, SP, Brasil.
Antonio José GonçalvesDisciplina de Cirurgia de Cabeça e Pescoço, Departamento de Cirurgia, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, SP, Brasil.
Jonathon Owen RusselHead and Neck Endocrine Surgery, Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, USA.
Ralph Patrick TufanoHead and Neck Endocrine Surgery, Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, USA.
Faculdade de Ciências Médicas da Santa Casa de São Paulo · BRAC Camargo Hospital · BRJohns Hopkins University · USUniversidade do Estado do Rio de Janeiro · BRCommunity University of Chapecó Region - Unochapecó · BRHospital Central da Polícia Militar · BRInstituto Nacional de Câncer - INCA · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to address the first cases of TOETVA done in Brazil, by TOETVA-Bra study group, regarding safety and complications.

methodsSeries of the first 93 TOETVAs cases in Brazil. All authors except LPK, AJG JOR and RPT received TOETVA training including cadaveric hands-on in Thailand or United States (Johns Hopkins Medicine) during 2017. After they came back to Brazil and started doing their first TOETVA cases in the cities of Rio de Janeiro, Sao Paulo and Chapecó they agreed to collaborate and gather data using an online spreadsheet. All patients were submitted to the technique described by Anuwong.

resultsA total of 93 patients underwent TOETVA. Most patients (58.1%) were submitted to total thyroidectomy and 59.1% had benign disease. Two patients (2.2%) needed conversion to open surgery. Five patients (9.3%) developed transient hypoparathyroidism and there were 3 (2.0%) temporary recurrent laryngeal nerve palsy. There was one (0.7%) permanent unilateral palsy. Twenty patients had some sort of complication, 16.1% were minor and 5.4% were major. A total of 73 patients (78.5%) had an uneventful recovery.

conclusionThe technique is reproducible with a low complication rate. While further studies are needed to confirm equivalency, early efforts suggest that TOETVA is not inferior to traditional open thyroidectomy in appropriately selected patients.

Indexed as

HypoparathyroidismThyroidectomyBrazilEndoscopyHumansLearning CurveendoscopicgoitersurgeryThyroid cancerthyroidectomy

Identifiers

PMID34191415
PMCPMC10065341
OpenAlexW3175571207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.