Evidence map›Paper›PMID 34191360›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2022

State of the mineralized tissue comprising the femoral ACL enthesis in young women with an ACL failure.

Daniella M Patton, Danielle N Ochocki, Colin T Martin, Michael Casden, Karl J Jepsen, James A Ashton-Miller, Edward M Wojtys, Stephen H Schlecht

Open access · bronzeAbstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daniella M PattonDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-2693-7905
Danielle N OchockiDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Colin T MartinDepartment of Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Michael CasdenSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, USA.
Karl J JepsenDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan, USA.
James A Ashton-MillerDepartment of Biomedical Engineering, Ann Arbor, Michigan, USA.
Edward M WojtysDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Stephen H SchlechtDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-6857-927X
University of Michigan · USIndiana University School of Medicine

Funding

Structure, Composition, & Histology Core - Core BP30AR069620 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KARL J JEPSEN · 2016 to 2026
$8.4M
GENETIC DETERMINATION OF SKELETAL FRAGILITYR01AR044927 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JEPSEN, KARL J · 2002 to 2014
$4.3M
New Perspectives on ACL InjuryR01AR054821 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ASHTON-MILLER, JAMES ANTHONY, WOJTYS, EDWARD M · 2007 to 2021
$3.1M
Bone Robustness as a Biomarker of Skeletal Aging and FragilityR01AR065424 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JEPSEN, KARL J · 2014 to 2018
$2.4M
Natural Variation in the Growth and Development of the ACL ComplexR00AR070903 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI SCHLECHT, STEPHEN · 2019 to 2021
$739k
GENETIC DETERMINATION OF SKELETAL FRAGILITYR29AR044927 · NIAMS · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI JEPSEN, KARL J · 1998 to 2002
$268k
Natural Variation in the Growth and Development of the ACL ComplexK99AR070903 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLECHT, STEPHEN · 2017 to 2018
$184k
NIAMS NIH HHS K99 AR070903NIAMS NIH HHS L40 AR072482NIAMS NIH HHS P30 AR069620NIAMS NIH HHS R00 AR070903NIAMS NIH HHS R01 AR044927NIAMS NIH HHS R01 AR054821NIAMS NIH HHS R01 AR065424NIAMS NIH HHS R29 AR044927
6 · The paper itself

Abstract

Despite poor graft integration among some patients that undergo an anterior cruciate ligament (ACL) reconstruction, there has been little consideration of the bone quality into which the ACL femoral tunnel is drilled and the graft is placed. Bone mineral density of the knee decreases following ACL injury. However, trabecular and cortical architecture differences between injured and non-injured femoral ACL entheses have not been reported. We hypothesize that injured femoral ACL entheses will show significantly less cortical and trabecular mass compared with non-injured controls. Femoral ACL enthesis explants from 54 female patients (13-25 years) were collected during ACL reconstructive surgery. Control explants (n = 12) were collected from seven donors (18-36 years). Injured (I) femoral explants differed from those of non-injured (NI) controls with significantly less (p ≤ 0.001) cortical volumetric bone mineral density (vBMD) (NI: 736.1-867.6 mg/cm

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionAnterior Cruciate LigamentFemaleFemurHumansKnee JointACL injuryBonefemoral ACL enthesistime-from-injury

Identifiers

PMID34191360
PMCPMC8716678
OpenAlexW3176475166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.