ReviewCardiology and therapy2021
Ischemic Stroke and Sleep: The Linking Genetic Factors.
Review in Cardiology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Observational)
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)
Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Restless legs syndrome and periodic limb movements of sleep - the relationship with stroke and other cerebrovascular disease.Nature reviews. Neurology · 2026Review
- Stem Cells Run Like Clockwork for Stroke Therapeutics.Stem cell reviews and reports · 2025Article
- Evaluation of the Prevalence of Sleep Disorders and Their Association with Stroke: A Hospital-Based Retrospective Study.Journal of clinical medicine · 2025Article
- Study on the relationship between sleep-wake states and prognosis in patients with intracranial arterial stenosis and ischemic stroke.Frontiers in neurology · 2025Article
- Exploring the Mediating Role of Sleep Deficit-Related Functional Status in Subacute Stroke Survivors.Medicina (Kaunas, Lithuania) · 2024Article
- The Role of Circadian Rhythms in Stroke: A Narrative Review.Neurochemical research · 2024Review
- Circadian Factors in Stroke: A Clinician's Perspective.Cardiology and therapy · 2023Review
- The effects of acupuncture on sleep disorders and its underlying mechanism: a literature review of rodent studies.Frontiers in neuroscience · 2023Review
- Sleep and Stroke: Opening Our Eyes to Current Knowledge of a Key Relationship.Current neurology and neuroscience reports · 2022Review
- [Interaction between ischemic stroke risk loci identified by genome-wide association studies and sleep habits].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022Article
- Study of the Economic, Environmental, and Social Factors Affecting Chinese Residents' Health Based on Machine Learning.Frontiers in public health · 2022Article
- Identification of Novel Genetic Variants Associated with Insomnia and Migraine Comorbidity.Nature and science of sleep · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review summarizes the available data about genetic factors which can link ischemic stroke and sleep. Sleep patterns (subjective and objective measures) are characterized by heritability and comprise up to 38-46%. According to Mendelian randomization analysis, genetic liability for short sleep duration and frequent insomnia symptoms is associated with ischemic stroke (predominantly of large artery subtype). The potential genetic links include variants of circadian genes, genes encoding components of neurotransmitter systems, common cardiovascular risk factors, as well as specific genetic factors related to certain sleep disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.