Evidence map›Paper›PMID 34191219›Full record

ArticleInternal and emergency medicine2022

Associations between CT pulmonary opacity score on admission and clinical characteristics and outcomes in patients with COVID-19.

Huanyuan Luo, Yuancheng Wang, Songqiao Liu, Ruoling Chen, Tao Chen, Yi Yang, Duolao Wang, Shenghong Ju

Abstract read
In one paragraph

Article in Internal and emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huanyuan Luo *Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.ORCID http://orcid.org/0000-0002-1898-4103
Yuancheng Wang *Department of Radiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Songqiao Liu *Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Ruoling ChenFaculty of Education, Health and Wellbeing, University of Wolverhampton, Wolverhampton, WV1 1LY, UK.
Tao ChenDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK.
Yi YangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China.
Duolao WangDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, L3 5QA, UK. Duolao.wang@lstmed.ac.uk.
Shenghong JuDepartment of Radiology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, China. jsh0836@hotmail.com.

Funding

Ministry of Science and Technology of the People's Republic of China 2020YFC0843700 67
6 · The paper itself

Abstract

This study investigated associations between chest computed tomography (CT) pulmonary opacity score on admission and clinical features and outcomes in COVID-19 patients. The retrospective multi-center cohort study included 496 COVID-19 patients in Jiangsu province, China diagnosed as of March 15, 2020. Patients were divided into four groups based on the quartile of pulmonary opacity score: ≤ 5%, 6-20%, 21-40% and 41% +. CT pulmonary opacity score was independently associated with age, single onset, fever, cough, peripheral capillary oxygen saturation, lymphocyte count, platelet count, albumin level, C-reactive protein (CRP) level and fibrinogen level on admission. Patients with score ≥ 41% had a dramatic increased risk of severe or critical illness [odds ratio (OR), 15.58, 95% confidence interval (CI) 3.82-63.53), intensive care unit (ICU)] admission (OR, 6.26, 95% CI 2.15-18.23), respiratory failure (OR, 19.49, 95% CI 4.55-83.40), and a prolonged hospital stay (coefficient, 2.59, 95% CI 0.46-4.72) compared to those with score ≤ 5%. CT pulmonary opacity score on admission, especially when ≥ 41%, was closely related to some clinical characteristics and was an independent predictor of disease severity, ICU admission, respiratory failure and long hospital stay in patients with COVID-19.

Indexed as

COVID-19Cohort StudiesHumansRetrospective StudiesSARS-CoV-2Tomography, X-Ray Computed2019-nCoVCoronavirusCOVID-19CTPrognosisPulmonary opacity

Identifiers

PMID34191219
PMCPMC8243308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.