ReviewEuropean journal of hybrid imaging2019
Does quantification have a role to play in the future of bone SPECT?
Review in European journal of hybrid imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Quantification in bone SPECT/CT.Frontiers in nuclear medicine · 2026Review
- The use of SPECT-CT in the evaluation of lumbar spine pathology - A Narrative Review.Brain & spine · 2026Review
- Utility of Quantitative and Semi-Quantitative SPECT/CT Metrics in Differentiating Mueller-Weiss Syndrome.Diagnostics (Basel, Switzerland) · 2025Article
- AI in SPECT Imaging: Opportunities and Challenges.Seminars in nuclear medicine · 2025Review
- Whole-Body SPECT/CT: Protocol Variation and Technical Consideration-A Narrative Review.Diagnostics (Basel, Switzerland) · 2024Review
- Technological Advances in SPECT and SPECT/CT Imaging.Diagnostics (Basel, Switzerland) · 2024Review
- Quantitative vs. Qualitative SPECT-CT Diagnostic Accuracy in Bone Lesion Evaluation-A Review of the Literature.Diagnostics (Basel, Switzerland) · 2023Review
- Quantification of bone metabolic activity in the natural course of fractural lesions measured by quantitative SPECT/CT.Asia Oceania journal of nuclear medicine & biology · 2023Article
- Standardized Uptake Value from Semiquantitative Bone Single-Photon Emission Computed Tomography/Computed Tomography in Normal Thoracic and Lumbar Vertebrae of Breast Cancer Patients.Asian spine journal · 2020Article
- Phantom and clinical evaluation of bone SPECT/CT image reconstruction with xSPECT algorithm.EJNMMI research · 2020Article
- An alternative method for radioactivity measurement in quantitative bone SPECT/CT imaging.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Routinely, there is a visual basis to nuclear medicine reporting: a reporter subjectively places a patient's condition into one of multiple discrete classes based on what they see. The addition of a quantitative result, such as a standardised uptake value (SUV), would provide a numerical insight into the nature of uptake, delivering greater objectivity, and perhaps improved patient management.For bone scintigraphy in particular quantification could increase the accuracy of diagnosis by helping to differentiate normal from abnormal uptake. Access to quantitative data might also enhance our ability to characterise lesions, stratify and monitor patients' conditions, and perform reliable dosimetry for radionuclide therapies. But is there enough evidence to suggest that we, as a community, should be making more effort to implement quantitative bone SPECT in routine clinical practice?We carried out multiple queries through the PubMed search engine to facilitate a cross-sectional review of the current status of bone SPECT quantification. Highly cited papers were assessed in more focus to scrutinise their conclusions.An increasing number of authors are reporting findings in terms of metrics such as SUV
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.