Evidence map›Paper›PMID 34191208›Full record

ArticleLasers in medical science2022

Combination effect of red light irradiation and Traychspermum ammi essential oil on colorectal cancer cells (SW480).

Khatereh Khorsandi, Zahra Kianmehr, Elmira Ghelichkhani

Abstract read
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In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Khatereh KhorsandiDepartment of Photodynamic, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran. khorsandi.kh@ut.ac.ir.
Zahra KianmehrDepartment of Biochemistry, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran. z.kianmehr1@gmail.com.
Elmira GhelichkhaniDepartment of Biochemistry, Faculty of Biological Science, North Tehran Branch, Islamic Azad University, Tehran, Iran.
Islamic Azad University North Tehran Branch · IRAcademic Center for Education, Culture and Research · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colon cancer is the third significant reason for death related to cancers in the world. There are various treatments for colon cancer, which have several side effects. Polyphenol agents are a type of antioxidant in plants that have diverse biological properties, such as anti-cancer effects. Here, we investigate the effect of Trachyspermum ammi essential oil (TEO) and red light irradiation on the colorectal cancer cell line (SW 480). The colorectal cancer cell lines were irradiated at 660 nm for 90 s and then the cells were incubated with different TEO concentrations. In another study, cells initially were treated with various TEO concentrations and then irradiation for 90 s. Effect of TEO and the red light irradiation on viability of the cell, ROS generation, and cell cycle was assessed by MTT and flow cytometry, respectively. The findings demonstrated that early incubation with TEO and then irradiation decreased the SW 480 cells survival more than the early irradiation at 660 nm and then essential oil. In addition, TEO treatment at IC

Indexed as

AmmiColonic NeoplasmsOils, VolatileAntioxidantsCell SurvivalHumansAntioxidantsOils, VolatileCell cycle arrestColorectal cancerLow-level laser therapy (LLLT)ROS generationTrachyspermum ammi essential oil

Identifiers

PMID34191208
OpenAlexW3173460370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.