Evidence map›Paper›PMID 34191175›Full record

ArticleEuropean journal of hybrid imaging2019

Hybrid FDG-PET/MR imaging of chronic osteomyelitis: a prospective case series.

Dennis Jan Willem Hulsen, Jan Geurts, Jacobus J Arts, Daan Loeffen, Cristina Mitea, Stefan Adrian Vöö

Open access · goldAbstract read
In one paragraph

Article in European journal of hybrid imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. [American journal of nuclear medicine and molecular imaging · 2026
    Review
  3. [Osteomyelitis in adults].Radiologie (Heidelberg, Germany) · 2025
    Review
  4. Diagnostic Performance of IntegratedWorld journal of nuclear medicine · 2025
    Article
  5. Current Concepts of Fracture-Related Infection.International journal of clinical practice · 2023
    Review
  6. Article
  7. MRI techniques for immunotherapy monitoring.Journal for immunotherapy of cancer · 2022
    Review
  8. Article
  9. PET/MRI in Pediatric Neuroimaging: Primer for Clinical Practice.AJNR. American journal of neuroradiology · 2022
    Review
  10. Review
  11. Imaging update on musculoskeletal infections.Journal of clinical orthopaedics and trauma · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dennis Jan Willem HulsenDepartment of Orthopaedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, The Netherlands. d.hulsen@jbz.nl.ORCID http://orcid.org/0000-0002-0850-1999
Jan GeurtsDepartment of Orthopaedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-0973-572X
Jacobus J ArtsDepartment of Orthopaedic Surgery, Research School CAPHRI, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-2947-8564
Daan LoeffenDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.
Cristina MiteaDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0001-5885-957X
Stefan Adrian VööDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0002-3432-1334
Maastricht University Medical Centre · NLUniversity College Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMagnetic resonance imaging (MRI) and 2-[18F]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography paired with computed tomography (PET/CT) are two commonly used imaging modalities in the complicated diagnostic workup of osteomyelitis. Diagnosis using these modalities relies on, respectively, anatomical (MRI) and metabolic (PET) signs. With hybrid PET/MRI being recently available, our goal is to qualitatively compare hybrid FDG PET/MRI to FDG PET/CT in the diagnosis and operative planning of chronic osteomyelitis.

methodsFive patients with suspected chronic osteomyelitis in an extremity underwent an

resultsThe consensus diagnoses based on PET/MRI and PET/CT images were identical for all five patients. One discrepancy between PET/MRI and PET/CT was found in the assessment of the features in one patient. PET signal intensities and target-to-background ratios were on average highest for PET/MRI. On PET/MRI, the location of infection based on FDG uptake could clearly be correlated with certain soft tissue structures (oedema, fluid collection, or muscle), which is paramount for surgical planning.

conclusionsIn the presented cases, FDG PET/MRI led to the same diagnosis and provided at least the same diagnostic information as PET/CT. PET/MRI was able to provide additional soft-tissue information for the physician planning treatment. Because of this, we suggest that PET/MRI could be used for osteomyelitis diagnosis and treatment planning.

Indexed as

DiagnosisOperative planningOsteomyelitisPET/MRI

Identifiers

PMID34191175
PMCPMC8218079
OpenAlexW2947180109

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.