Evidence map›Paper›PMID 34191159›Full record

ArticleEuropean journal of hybrid imaging2019

Ability of artificial intelligence to diagnose coronary artery stenosis using hybrid images of coronary computed tomography angiography and myocardial perfusion SPECT.

Hiroto Yoneyama, Kenichi Nakajima, Junichi Taki, Hiroshi Wakabayashi, Shinro Matsuo, Takahiro Konishi, Koichi Okuda, Takayuki Shibutani, Masahisa Onoguchi, Seigo Kinuya

Abstract read
In one paragraph

Article in European journal of hybrid imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Technological Advances in SPECT and SPECT/CT Imaging.Diagnostics (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Quantitative clinical nuclear cardiology, part 2: Evolving/emerging applications.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Review
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroto YoneyamaDepartment of Radiological Technology, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa, 920-8641, Japan. kizu@cf6.so-net.ne.jp.ORCID http://orcid.org/0000-0001-5213-6223
Kenichi NakajimaDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Junichi TakiDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Hiroshi WakabayashiDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Shinro MatsuoDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.
Takahiro KonishiDepartment of Radiological Technology, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.
Koichi OkudaDepartment of Physics, Kanazawa Medical University, Kahoku, Japan.
Takayuki ShibutaniDepartment of Quantum Medical Technology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Masahisa OnoguchiDepartment of Quantum Medical Technology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
Seigo KinuyaDepartment of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDetecting culprit coronary arteries in patients with ischemia using only myocardial perfusion single-photon emission computed tomography (SPECT) can be challenging. This study aimed to improve the detection of culprit regions using an artificial neural network (ANN) to analyze hybrid images of coronary computed tomography angiography (CCTA) and myocardial perfusion SPECT.

methodsThis study enrolled 59 patients with stable coronary artery disease (CAD) who had been assessed by coronary angiography within 60 days of myocardial perfusion SPECT. Two nuclear medicine physicians interpreted the myocardial perfusion SPECT and hybrid images with four grades of confidence, then drew regions on polar maps to identify culprit coronary arteries. The gold standard was determined by the consensus of two other nuclear cardiology specialist based on coronary angiography findings and clinical information. The ability to detect culprit coronary arteries was compared among experienced nuclear cardiologists and the ANN. Receiver operating characteristics (ROC) curves were analyzed and areas under the ROC curves (AUC) were determined.

resultsUsing hybrid images, observer A detected CAD in the right (RCA), left anterior descending (LAD), and left circumflex (LCX) coronary arteries with 83.6%, 89.3%, and 94.4% accuracy, respectively and observer B did so with 72.9%, 84.2%, and 89.3%, respectively. The ANN was 79.1%, 89.8%, and 89.3% accurate for each coronary artery. Diagnostic accuracy was comparable between the ANN and experienced nuclear medicine physicians. The AUC was significantly improved using hybrid images in the RCA region (observer A: from 0.715 to 0.835, p = 0.0031; observer B: from 0.771 to 0.843, p = 0.042). To detect culprit coronary arteries in perfusion defects of the inferior wall without using hybrid images was problematic because the perfused areas of the LCX and RCA varied among individuals.

conclusionsHybrid images of CCTA and myocardial perfusion SPECT are useful for detecting culprit coronary arteries. Diagnoses using artificial intelligence are comparable to that by nuclear medicine physicians.

Indexed as

Cardiac evaluationComputer-aided diagnosisIschemiaNeural networkNuclear cardiology

Identifiers

PMID34191159
PMCPMC8212308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.