ArticleJournal of materials science. Materials in medicine2021
Stable sol-gel hydroxyapatite coating on zirconia dental implant for improved osseointegration.
Article in Journal of materials science. Materials in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
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Who cites it
13 citing papers in PubMed.
- When bioactivity comes at a mechanical cost: toward mechanically safe bioactivation of zirconia dental implants.Bioactive materials · 2027Review
- Cellular Responses at the Zirconia Dental Implant Interface: A Comprehensive Review.Journal of functional biomaterials · 2026Review
- Digital Manufacturing of Calcium Phosphate-Based Dental Materials: From Design to Clinical Use.Materials (Basel, Switzerland) · 2026Review
- Enhancing Osseointegration of Zirconia Implants Using Calcium Phosphate Coatings: A Systematic Review.Materials (Basel, Switzerland) · 2025Review
- State of Art and Perspective of Calcium Phosphate-Based Coatings Coupled with Bioactive Compounds for Orthopedic Applications.Nanomaterials (Basel, Switzerland) · 2025Review
- The Future of Dental Implants: A Narrative Review of Trends, Technologies, and Patient Considerations.Cureus · 2025Review
- Advanced Strategies for Enhancing the Biocompatibility and Antibacterial Properties of Implantable Structures.Materials (Basel, Switzerland) · 2025Review
- Applications of Bioactive Strontium Compounds in Dentistry.Journal of functional biomaterials · 2024Review
- Influence of surface texturing and coatings on mechanical properties and integration with bone tissue: an in silico study.Frontiers in bioengineering and biotechnology · 2024Article
- Improvement of mechanical and antibacterial properties of porous nHA scaffolds by fluorinated graphene oxide.RSC advances · 2022Article
- HowMaterials (Basel, Switzerland) · 2022Review
- Efficiency of Nanohydroxyapatite on Repairing Type II Diabetes Dental Implant-Bone Defect.BioMed research international · 2022Article
- Evaluation of antibacterial property and biocompatibility of Cu doped TiOFrontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Aside from being known for its excellent mechanical properties and aesthetic effect, zirconia has recently attracted attention as a new dental implant material. Many studies have focused on hydroxyapatite (HA) coating for obtaining improved biocompatibility, however the coating stability was reduced by a byproduct produced during the high-temperature sintering process. In this study, to overcome this problem, we simply coated the zirconia surface with a sol-gel-derived hydroxyapatite (HA) layer and then sintered it at a varied temperature (<1000 °C). The surface showed a nanoporous structure, and there was no crystalline phase other than HA and zirconia when the sintering temperature was 800 °C. The adhesion strength of the HA layer (>40 MPa) was also appropriate as a dental implant application. In addition, in vitro cell experiments using a preosteoblast cell line revealed that the HA-coated zirconia surface acts as a preferable surface for cell attachment and proliferation than bare zirconia surface. In vivo animal experiments also demonstrated that the osteoconductivity of zirconia were dramatically enhanced by HA coating, which was comparable to that of Ti implant. These results suggest that the sol-gel-based HA-coated zirconia has a great potential for use as a dental implant material.
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Registered trials
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