Evidence map›Paper›PMID 34191132›Full record

ArticleThe ultrasound journal2021

B-line quantification: comparing learners novice to lung ultrasound assisted by machine artificial intelligence technology to expert review.

Frances M Russell, Robert R Ehrman, Allen Barton, Elisa Sarmiento, Jakob E Ottenhoff, Benjamin K Nti

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The ultrasound journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06377449 (Influence of Ultrasound Examination of the Lungs on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients), which is not on this map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06377449 narecruitingnot on this mapstarted 2024, after this paper: background citation

Influence of Ultrasound Examination of the Lungs on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

TypeinterventionalSponsorSaint Petersburg State University, RussiaRan2024 to 2026Enrolled186ConditionsIschemic Heart Disease, Aortic Stenosis, Severe, Aortic Insufficiency, Mitral StenosisArmsUltrasound examination of the lungs
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 41 citations in OpenAlex.

  1. Observational
  2. Evolving role of point-of-care ultrasound in prehospital emergency care: a narrative review.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
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  10. Article
  11. Article
  12. To B or not to B-lines.Journal of anesthesia, analgesia and critical care · 2024
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Deep Learning for Detection and Localization of B-Lines in Lung Ultrasound.IEEE journal of biomedical and health informatics · 2023
    Article
  19. The Incremental Role of Multiorgan Point-of-Care Ultrasounds in the Emergency Setting.International journal of environmental research and public health · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Frances M RussellDepartment of Emergency Medicine, Indiana University School of Medicine, 720 Eskenazi Ave, FOB 3rd Floor, Indianapolis, IN, 46202, USA. framruss@iu.edu.ORCID http://orcid.org/0000-0003-2756-7392
Robert R EhrmanDepartment of Emergency Medicine, Wayne State University School of Medicine, 4021 St Antoine Ave, Suite 6G, Detroit, MI, 48201, USA.
Allen BartonBoone County Emergency Physicians, Zionsville, IN, 46077, USA.
Elisa SarmientoDepartment of Emergency Medicine, Indiana University School of Medicine, 720 Eskenazi Ave, FOB 3rd Floor, Indianapolis, IN, 46202, USA.
Jakob E OttenhoffDepartment of Emergency Medicine, Wayne State University School of Medicine, 4021 St Antoine Ave, Suite 6G, Detroit, MI, 48201, USA.
Benjamin K NtiDepartment of Emergency Medicine, Indiana University School of Medicine, 720 Eskenazi Ave, FOB 3rd Floor, Indianapolis, IN, 46202, USA.
Indiana University School of MedicineWayne State University · USBoone County Health Department · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe goal of this study was to assess the ability of machine artificial intelligence (AI) to quantitatively assess lung ultrasound (LUS) B-line presence using images obtained by learners novice to LUS in patients with acute heart failure (AHF), compared to expert interpretation.

methodsThis was a prospective, multicenter observational study conducted at two urban academic institutions. Learners novice to LUS completed a 30-min training session on lung image acquisition which included lecture and hands-on patient scanning. Learners independently acquired images on patients with suspected AHF. Automatic B-line quantification was obtained offline after completion of the study. Machine AI counted the maximum number of B-lines visualized during a clip. The criterion standard for B-line counts was semi-quantitative analysis by a blinded point-of-care LUS expert reviewer. Image quality was blindly determined by an expert reviewer. A second expert reviewer blindly determined B-line counts and image quality. Intraclass correlation was used to determine agreement between machine AI and expert, and expert to expert.

resultsFifty-one novice learners completed 87 scans on 29 patients. We analyzed data from 611 lung zones. The overall intraclass correlation for agreement between novice learner images post-processed with AI technology and expert review was 0.56 (confidence interval [CI] 0.51-0.62), and 0.82 (CI 0.73-0.91) between experts. Median image quality was 4 (on a 5-point scale), and correlation between experts for quality assessment was 0.65 (CI 0.48-0.82).

conclusionAfter a short training session, novice learners were able to obtain high-quality images. When the AI deep learning algorithm was applied to those images, it quantified B-lines with moderate-to-fair correlation as compared to semi-quantitative analysis by expert review. This data shows promise, but further development is needed before widespread clinical use.

Indexed as

Acute heart failureArtificial intelligenceLung ultrasoundNovice learnerPoint-of-care ultrasound

Identifiers

PMID34191132
PMCPMC8245599
OpenAlexW3176644691

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.